Acclarent
Acquisition in 2023
Acclarent, Inc. is a medical device company focused on developing innovative technologies for ear, nose, and throat (ENT) patients. The company specializes in balloon sinuplasty devices, which are minimally invasive tools designed to assist physicians in treating chronic sinusitis. These devices enable doctors to navigate sinus anatomy effectively, facilitating the opening of blocked sinus ostia and passageways to promote proper sinus drainage. Acclarent's Balloon Sinuplasty technology and associated Relieva product portfolio provide alternatives to traditional endoscopic surgical methods. The company's devices received FDA clearance and were commercially launched in the United States in 2005, marking a significant advancement in the treatment options available for patients with sinus-related conditions.
Surgical Innovation Associates
Acquisition in 2022
Surgical Innovation Associates, Inc. is a medical device company focused on developing innovative solutions for surgical procedures, particularly in plastic and reconstructive surgery. Founded in 2014 and headquartered in Chicago, Illinois, the company aims to enhance patient care and reduce costs through its "for surgeon, by surgeon" approach to implantable devices. Its flagship product, DuraSorb® Monofilament Mesh, is designed for soft tissue reinforcement and is US FDA 510(k) cleared and CE marked. Made from polydioxanone, this mesh addresses limitations of existing soft tissue support products by minimizing bacterial adhesion and supporting natural tissue recovery during the healing process. Surgical Innovation Associates serves a global market, providing solutions that meet critical clinical needs in the surgical field. The company's commitment to innovation is further supported by its proximity to leading healthcare institutions and academic resources.
ACell, Inc. is a Maryland-based company founded in 1999 that specializes in the development and commercialization of extracellular matrix devices designed to repair and remodel damaged tissues and organs. The company’s MatriStem technology features a non-crosslinked, resorbable, and acellular material used in various surgical procedures. ACell offers a range of products, including the MatriStem Wound Care Matrix for regenerative treatment of wounds, the MatriStem Plastic Surgery Matrix for plastic surgery applications, and the MatriStem Hernia Matrix for general surgical needs. These devices are utilized in acute care settings to enhance healing and reinforce soft tissue surgical defects. Additionally, ACell operates a manufacturing facility in Lafayette, Indiana.
Rebound Therapeutics
Acquisition in 2019
Rebound Therapeutics Corp. is a medical device company based in Irvine, California, focused on developing single-use, disposable devices that enhance access, imaging, and illumination during minimally invasive surgical procedures. Established in 2015, the company has made significant strides in product development, creating a unique range of devices aimed at improving procedural and clinical outcomes in various surgical fields, including neurosurgery, spine, orthopedic, thoracic, and general abdominal surgeries. Rebound Therapeutics has assembled a distinguished Scientific Advisory Board of leading physicians in minimally invasive surgery and has filed 14 patents to protect its innovative technologies. The company is also preparing for initial human-use trials following a series of successful pre-clinical studies. As of September 2019, Rebound operates as a subsidiary of Integra LifeSciences Holdings Corporation.
Arkis BioSciences
Acquisition in 2019
Arkis BioSciences Inc. specializes in the development and manufacturing of surgical tools and implantable devices aimed at treating conditions such as intracranial hypertension, traumatic brain injury, hemorrhagic stroke, and hydrocephalus. The company focuses on creating advanced catheters and minimally invasive instruments for neurosurgery, incorporating proprietary technologies like Endexo, which helps reduce complications associated with catheter use. Notable products include the Arkis Tunneling Guidewire, which streamlines ventriculoperitoneal shunt procedures, and anti-thrombogenic catheters designed to prevent obstructions. Founded in 2011 and based in Knoxville, Tennessee, Arkis BioSciences is dedicated to enhancing surgical techniques, thereby minimizing patient trauma, decreasing surgical times, and improving overall treatment outcomes. As of 2019, Arkis operates as a subsidiary of Integra LifeSciences Holdings Corporation.
Codman Neuro
Acquisition in 2017
Codman Neuro is a global neurosurgery and neurovascular company that offers a broad portfolio of devices for hydrocephalus management, neuro intensive care and cranial surgery, as well as aneurysm coils, vascular reconstruction devices and other technologies used in the endovascular treatment of cerebral aneurysms and stroke. Codman Neuro is part of DePuy Synthes Companies of Johnson & Johnson.
TGX Medical Systems
Acquisition in 2017
TGX Medical Systems specializes in the design, development, and marketing of software solutions for medical asset management and tracking. The company offers web-based systems that integrate with specialized hardware provided by major integrators. TGX Medical Systems caters to a diverse clientele, including small, medium, and large hospitals and medical facilities. Its products stand out in the market due to their sophisticated interfaces, scalability, and ease of modification, supported by an extensive portfolio of patents.
Derma Sciences
Acquisition in 2017
Derma Sciences, Inc. is a specialty medical device and pharmaceutical company based in Plainsboro, New Jersey, focused on wound care. The company is a fully integrated manufacturer, marketer, and supplier of a comprehensive range of products in various categories, including advanced wound care, traditional wound care, burn care, skin care, specialty securement and closure devices, and first aid. Derma Sciences operates two manufacturing facilities located in Toronto and China, which also provide contract manufacturing services for original equipment manufacturers or private label products. The company’s offerings are particularly utilized in the treatment of diabetic foot ulcers and for wound care dressings, emphasizing its commitment to addressing critical healthcare needs.
Tekmed Instruments
Acquisition in 2015
Tekmed Instruments is a privately held company that specializes in the manufacture and distribution of medical devices, particularly targeting the fields of neurosurgery and neurotrauma. In addition to its product offerings, Tekmed provides comprehensive services, including maintenance and repair of biomedical equipment across various surgical specialties. These specialties encompass plastic and reconstructive surgery, cardiovascular surgery, image diagnostics, general surgery, anesthesia, intensive care, interventional radiology, and proton therapy. Through its focus on advanced medical technologies and support services, Tekmed Instruments aims to enhance the quality and efficiency of healthcare delivery.
TEI Biosciences
Acquisition in 2015
TEI Biosciences is a medical device company focused on developing biological products for soft tissue repair and reinforcement applications. The company specializes in the creation and manufacturing of medical implants and biopharmaceutical agents designed to repair or replace tissues and organs that have deteriorated due to aging, injury, or disease. With a commitment to advancing the field of plastic and reconstructive surgery, TEI Biosciences aims to provide innovative solutions that enhance patient outcomes in various medical contexts.
Medtronic Xomed Instrumentation SAS
Acquisition in 2014
Medtronic Xomed Instrumentation SAS is a privately held company that specializes in manual ear, nose, and throat instruments and designs, manufactures, and sells reusable handheld instruments to ENT and laparoscopic surgical specialists around the world.
Avraham Pharmaceuticals
Venture Round in 2014
Avraham Pharmaceuticals Ltd. is a privately held pharmaceutical company based in Yavne, Israel, founded in 2010. The company focuses on the development of innovative products for the treatment and prevention of neurodegenerative disorders. Its lead product candidate, Ladostigil, is designed for mild cognitive impairment and employs a combination of neuroprotective mechanisms, including the reduction of oxidative stress, inhibition of pro-inflammatory cytokines, and modulation of microglial activation. Avraham Pharmaceuticals has raised funding to support clinical trials, including a European Phase II proof-of-concept efficacy trial for Alzheimer's disease, aimed at validating the effectiveness of Ladostigil.
Confluent Surgical
Acquisition in 2014
Confluent Surgical develops products to address the need for surgical sealing and post-surgical adhesion prevention applications.The company provides DuraSeal, an adjunct to sutured dural repair during cranial surgeries to provide watertight closure. The company was founded in 1998 and is headquartered in Waltham, Massachusetts.
Tarsus Medical
Acquisition in 2013
Tarsus Medical Inc. develops solutions and devices for unsolved problems within the field of podiatry. The company was founded in 2009 and is based in Menlo Park, California. As of January 24, 2013, Tarsus Medical Inc. operates as a subsidiary of Integra LifeSciences Holdings Corporation.
Ascension Orthopedics
Acquisition in 2011
Ascension Orthopedics is a manufacturer of orthopedic products designed to alleviate pain and dysfunction in patients, focusing on both upper and lower limb applications. The company's product portfolio includes joint replacement implants for various body parts, such as the shoulder, elbow, wrist, hand, foot, soft tissue, and ankle. Founded in 1992 and headquartered in Austin, Texas, Ascension Orthopedics serves both the domestic and international markets. In 2011, the company was acquired by Integra LifeSciences, further enhancing its capabilities in the orthopedic sector.
Innovative Spinal Technologies
Acquisition in 2009
Innovative Spinal Technologies is a spine technology company based in Mansfield, Massachusetts, established in 2002. The company specializes in the development of motion preservation and minimally invasive treatments for spinal disorders. Its product portfolio includes the AXIENT Dynamic Fixation system, a pedicle screw-based motion system, and the PARAMOUNT Lumbar Fusion System, designed for lumbar fusion procedures in various surgical approaches, including minimally invasive and open techniques. Additionally, the PARAMOUNT MIS Pedicle Screw System caters to both single and multi-level procedures, while the PARAMOUNT Open Pedicle Screw System is tailored for minimally invasive lumbar fusion. The PARAMOUNT VBR is specifically engineered for a minimally invasive transforaminal approach, reflecting the company’s commitment to advancing spinal care through innovative technologies.
Omni-Tract
Acquisition in 2008
Omni-Tract is a privately held company that design, development, manufacture, and distribution of table-mounted surgical retractor systems.
Integra Neurosciences
Acquisition in 2008
Integra Neurosciences is a privately held company that distributes neurosurgical devices.
Theken Spine
Acquisition in 2008
Theken Spine designs, develops, manufactures, and distributes spinal fixation devices in the United States. It offers degenerative products, including coral pedicle screw system, a fusion implant system for the correction and stabilization of lumbar or lower region of the spine; and coral friction head screw system for fixation of deformity or degenerative spinal conditions in the thoraco-lumbar spine. Theken Spine also offers cervical products such as tether anterior cervical plating (ACP) system to provide the stabilization of cervical spine in the case of arthrodesis; atoll cervico-thoracic system to promote fusion for various patient anatomies; and manta ray ACP system that helps surgeons in controlling the plate construct intra-operatively. Moreover, it offers vertebral body (VBR) products that include L-POD and Vu C-POD to allow graft pack inside and around the implant; Vu L-POD PEEK-Optima VBR to match the anatomy of a vertebral endplate; Vu Mesh and Vu e-POD vertebral body replacement systems; and Vu aPOD, an anterior inter vertebral body fusion device. Further, Theken Spine offers deformity products comprising coral hook formputty, a beta-tricalcium phosphate putty to fill bone voids; trauma/tumor products consisting of X-POD to expand the Theken Spine portfolio with adjustable VBR construct; and bodyform thoracic and thoraco-lumbar fixation system to provide a fixation solution for spine regions from T1-L5, as well as offers synthetic bone substitute products. It markets its products through a network of independent distributors. Randy Theken founded Theken Spine August 1, 1998, with its headquarters in Akron in Ohio. It operates as a subsidiary of SeaSpine Holdings.
Theken Disc
Acquisition in 2008
Theken Disc is a privately held company that designs, develops, and manufactures spinal arthroplasty products.
Therics
Acquisition in 2008
Therics is a privately held company that designs, develops, and manufactures various synthetic bone substitute products.
Kinetikos Medical
Acquisition in 2006
Kinetikos Medical is a manufacturer of innovative orthopedic implants and surgical devices for small bone and joint procedures involving the foot, ankle, hand, wrist and elbow.
Miltex
Acquisition in 2006
Miltex is a manufacturer of surgical and dental hand instruments. The company supplies a wide range of products to physician offices, dental practices, veterinarian clinics, and ambulatory surgery care centers. Their surgical product line includes scissors, needle holders, forceps, retractors, jaws, scissor blades, rasps, dissectors, fiber optic and bipolar instrument patterns, surgical disposables, and sterilization containers made of stainless steel. Additionally, Miltex offers dental products such as hand instruments, hand and rotary files, accessory endodontic products, syringes, burs and diamonds, gauges and dividers, prosthodontic and restorative instruments, dressing forceps, elevators, rongeurs, hemostats, lab burs.