Integra Lifesciences

Integra LifeSciences Holdings Corporation (Integra) is an integrated medical device company. The products include implants, instruments and equipment for orthopedic surgery, neurosurgery and general surgery. Integra's orthopedic products include devices and implants for foot and ankle, hand and wrist, tendon and peripheral nerve protection and repair, wound repair and spine. Integra is a cranial neurosurgery, offering a portfolio of implants, devices, instruments and systems used in neurosurgery, neuromonitoring, neurotrauma, and related critical care. In the United States, Integra provides surgical instruments to hospitals, surgery centers and alternate care sites, including physician and dental offices. The Company sells products in three market categories: Orthopedics, Neurosurgery and Instruments. In May 2011, it acquired SeaSpine, Inc.

Lea Knight

CFO, Finance and Executive Vice President

23 past transactions

Acclarent

Acquisition in 2023
Acclarent, Inc. is a medical device company focused on developing innovative technologies for ear, nose, and throat (ENT) patients. The company's primary emphasis is on balloon sinuplasty devices, which are minimally invasive tools designed to assist physicians in treating chronic sinusitis. These devices enable doctors to navigate the sinus anatomy and open blocked sinus ostia and passageways, facilitating sinus drainage. Acclarent's Balloon Sinuplasty technology and the Relieva product portfolio provide alternatives to conventional endoscopic surgical methods. The company received FDA clearances for its devices in 2005 and launched them commercially in the United States that same year, marking a significant advancement in sinus surgery.

Surgical Innovation Associates

Acquisition in 2022
Surgical Innovation Associates, Inc. is a medical device company based in Chicago, Illinois, focused on developing innovative solutions for plastic, reconstructive, and general surgery. Founded in 2014, the company aims to enhance the standard of care while reducing systemic costs through its range of implantable devices. Its flagship product, DuraSorb® Monofilament Mesh, is designed for soft tissue reinforcement in surgical procedures and is US FDA 510(k) cleared and CE marked. The mesh, made from polydioxanone, features a unique design that minimizes bacterial adhesion and promotes healing by absorbing in alignment with the tissue's natural recovery. This allows for versatility in surgical applications, enabling surgeons to manipulate the mesh similarly to autologous tissue. Surgical Innovation Associates serves both domestic and international markets, addressing key clinical needs with a growing pipeline of novel medical devices.

ACell

Acquisition in 2020
ACell, Inc. engages in the development and commercialization of extracellular matrix devices to repair and remodel damaged tissues and organs in a range of surgical procedures for the U.S. and international patents. It offers MatriStem technology, a non-crosslinked, resorbable, and acellular material; MatriStem Wound Care Matrix, a wound care device with regenerative medicine technology; MatriStem Plastic Surgery Matrix, a plastic surgery and wound care device; and MatriStem Hernia Matrix, a general surgery device. The company was incorporated in 1999 and is headquartered in Columbia, Maryland. It has a manufacturing facility in Lafayette, Indiana.

Rebound Therapeutics

Acquisition in 2019
Rebound Therapeutics Corp. focuses on developing single-use, disposable medical devices aimed at enhancing access, imaging, and illumination during minimally invasive surgical procedures. Established in 2015 and headquartered in Irvine, California, the company has rapidly advanced its product line, offering innovative devices designed to improve procedural and clinical outcomes across various surgical specialties, including neurosurgery, spine and orthopedic surgery, and general abdominal surgery. Rebound has assembled a distinguished Scientific Advisory Board of leading minimally invasive surgery physicians and has filed 14 patents to protect its innovative technologies. The company has also completed several pre-clinical studies, paving the way for initial human-use trials that are set to begin soon. As of September 2019, Rebound Therapeutics operates as a subsidiary of Integra LifeSciences Holdings Corporation.

Arkis BioSciences

Acquisition in 2019
Arkis BioSciences develops, markets, and sells advanced catheters and minimally invasive instrumentation for neurosurgery. Arkis' proprietary catheters incorporate Endexo, intended to reduce catheter related complications, while the company's instrumentation is designed to be less invasive over a variety of neurosurgical procedures. Altogether, the company's portfolio enables healthcare practitioners the potential to reduce surgical trauma, shorten surgical duration, and reduce treatment complications.

Codman Neuro

Acquisition in 2017
Codman Neuro is a global neurosurgery and neurovascular company that offers a broad portfolio of devices for hydrocephalus management, neuro intensive care and cranial surgery, as well as aneurysm coils, vascular reconstruction devices and other technologies used in the endovascular treatment of cerebral aneurysms and stroke. Codman Neuro is part of DePuy Synthes Companies of Johnson & Johnson.

TGX Medical Systems

Acquisition in 2017
TGX Medical Systems specializes in the design, development, and marketing of software solutions for medical asset management and tracking. Their web-based systems integrate seamlessly with specialized hardware provided by major integrators, catering to the needs of small, medium, and large hospitals and medical facilities. TGX Medical Systems stands out from its competitors through its sophisticated interfaces, scalability, and ease of modification, which are supported by extensive patents.

Tekmed Instruments

Acquisition in 2015
Tekmed Instruments is a privately held company that specializes in manufacturing medical devices, with a particular focus on neurosurgery and neurotrauma. In addition to producing these devices, the company provides a range of services, including the maintenance and repair of biomedical equipment. Tekmed Instruments supports various medical fields, such as plastic and reconstructive surgery, cardiovascular surgery, image diagnostics, general surgery, anesthesia, intensive care, interventional radiology, and proton therapy. Through its comprehensive offerings, the company aims to enhance the effectiveness and safety of medical procedures.

TEI Biosciences

Acquisition in 2015
TEI Biosciences is a medical device company that provides plastic and reconstructive surgery components.

Medtronic Xomed Instrumentation SAS

Acquisition in 2014
Medtronic Xomed Instrumentation SAS is a privately held company that specializes in manual ear, nose, and throat instruments and designs, manufactures, and sells reusable handheld instruments to ENT and laparoscopic surgical specialists around the world.

Avraham Pharmaceuticals

Venture Round in 2014
Avraham Pharmaceuticals Ltd. is a privately held pharmaceutical company based in Yavne, Israel, established in 2010. The company focuses on developing innovative treatments for neurodegenerative disorders. Its lead product candidate, Ladostigil, is aimed at addressing mild cognitive impairment and is designed to incorporate neuroprotective mechanisms, including the reduction of oxidative stress and microglial activation, as well as the inhibition of pro-inflammatory cytokines. Avraham Pharmaceuticals has raised $9 million to support a European Phase II proof-of-concept efficacy trial for Ladostigil in patients with Alzheimer's disease.

Confluent Surgical

Acquisition in 2014
Confluent Surgical develops products to address the need for surgical sealing and post-surgical adhesion prevention applications.The company provides DuraSeal, an adjunct to sutured dural repair during cranial surgeries to provide watertight closure. The company was founded in 1998 and is headquartered in Waltham, Massachusetts.

Tarsus Medical

Acquisition in 2013
Tarsus Medical Inc. develops solutions and devices for unsolved problems within the field of podiatry. The company was founded in 2009 and is based in Menlo Park, California. As of January 24, 2013, Tarsus Medical Inc. operates as a subsidiary of Integra LifeSciences Holdings Corporation.

Ascension Orthopedics

Acquisition in 2011
Ascension Orthopedics produces and sells orthopedic products for the upper and lower limbs to help patients suffering from pain and dysfunction in the United States and internationally. Its joint replacement products include implants for the shoulder, elbow, wrist, hand, foot, soft tissue, and ankle applications. The company was founded in 1992 and is based in Austin, Texas. In 2011, the company was acquired by [Integra LifeSciences](/organization/integra-lifesciences-holdings).

Innovative Spinal Technologies

Acquisition in 2009
Innovative Spinal Technologies is a spine technology company based in Mansfield, Massachusetts, that specializes in developing motion preservation and minimally invasive treatments for spinal disorders. Founded in 2002, the company offers a range of products designed to enhance surgical outcomes in spinal procedures. Its AXIENT Dynamic Fixation system is a pedicle screw-based motion system, while the PARAMOUNT product line includes several systems tailored for lumbar fusion procedures. This includes the PARAMOUNT Lumbar Fusion System, which can be used in minimally invasive, mini-open, or open surgical techniques, as well as the PARAMOUNT MIS and Open Pedicle Screw Systems, designed for single and multi-level procedures. Additionally, the PARAMOUNT VBR is engineered for a minimally invasive transforaminal approach.

Omni-Tract

Acquisition in 2008
Omni-Tract is a privately held company that design, development, manufacture, and distribution of table-mounted surgical retractor systems.

Integra Neurosciences

Acquisition in 2008
Integra Neurosciences is a privately held company that distributes neurosurgical devices.

Theken Spine

Acquisition in 2008
Theken Spine designs, develops, manufactures, and distributes spinal fixation devices in the United States. It offers degenerative products, including coral pedicle screw system, a fusion implant system for the correction and stabilization of lumbar or lower region of the spine; and coral friction head screw system for fixation of deformity or degenerative spinal conditions in the thoraco-lumbar spine. Theken Spine also offers cervical products such as tether anterior cervical plating (ACP) system to provide the stabilization of cervical spine in the case of arthrodesis; atoll cervico-thoracic system to promote fusion for various patient anatomies; and manta ray ACP system that helps surgeons in controlling the plate construct intra-operatively. Moreover, it offers vertebral body (VBR) products that include L-POD and Vu C-POD to allow graft pack inside and around the implant; Vu L-POD PEEK-Optima VBR to match the anatomy of a vertebral endplate; Vu Mesh and Vu e-POD vertebral body replacement systems; and Vu aPOD, an anterior inter vertebral body fusion device. Further, Theken Spine offers deformity products comprising coral hook formputty, a beta-tricalcium phosphate putty to fill bone voids; trauma/tumor products consisting of X-POD to expand the Theken Spine portfolio with adjustable VBR construct; and bodyform thoracic and thoraco-lumbar fixation system to provide a fixation solution for spine regions from T1-L5, as well as offers synthetic bone substitute products. It markets its products through a network of independent distributors. Randy Theken founded Theken Spine August 1, 1998, with its headquarters in Akron in Ohio. It operates as a subsidiary of SeaSpine Holdings.

Theken Disc

Acquisition in 2008
Theken Disc is a privately held company that designs, develops, and manufactures spinal arthroplasty products.

Therics

Acquisition in 2008
Therics is a privately held company that designs, develops, and manufactures various synthetic bone substitute products.

Kinetikos Medical

Acquisition in 2006
Kinetikos Medical is a manufacturer of innovative orthopedic implants and surgical devices for small bone and joint procedures involving the foot, ankle, hand, wrist and elbow.

Miltex

Acquisition in 2006
Miltex is a manufacturer specializing in hand-held surgical and dental instruments. The company supplies a comprehensive range of products for use in physician, dental, and veterinary offices, as well as in ambulatory surgery centers. Its surgical offerings include scissors, needle holders, forceps, retractors, and various types of blades and jaws. Additionally, Miltex provides a selection of surgical disposables and sterilization containers made from stainless steel. In the dental sector, the company produces hand instruments, rotary files, endodontic accessories, syringes, burs, gauges, and restorative instruments, among others.
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