3×5 Partners

Kaleidoscope is a company that specializes in the design, administration, and hosting of branded scholarship and grant programs through a cloud-based marketplace. Founded in 2016 by Gregory Dehn and headquartered in Minneapolis, Minnesota, Kaleidoscope connects scholarship funders with students, facilitating a seamless marketplace that matches qualified candidates with personalized scholarship opportunities. The company’s platform is tailored to support organizations and advocates in their efforts to fund the next generation of leaders, artists, and entrepreneurs, emphasizing low administrative costs and student choice. By providing innovative and impactful program design, Kaleidoscope aims to enhance access to educational funding and streamline the scholarship management process.

Smart Wires is an electrical and electronics company founded in 2010 and headquartered in San Francisco, California. It specializes in grid optimization solutions, particularly for medium and high voltage electricity transmission grids. The company develops and manufactures modular power flow control technology devices designed to manage and direct power flow within high electric transmission systems. By utilizing advanced power electronics hardware and software, Smart Wires enhances and optimizes grid capacity, addressing challenges such as transmission reliability and congestion management in the evolving energy landscape.

Bonum Therapeutics is a biotechnology company focused on developing protein-based drugs aimed at treating various diseases, with a primary emphasis on cancer. The company has established a technology platform that enables the creation of drugs capable of sensing their local environment and transitioning from an inactive to an active form. This innovative approach allows for the development of therapeutics that can be tailored to respond to specific conditions, thereby enhancing the potential for effective treatment of diseases that currently lack viable cures. In addition to cancer, Bonum Therapeutics also targets metabolic diseases, immunological disorders, and pain management.

Fervo Energy, founded in 2017 and based in San Francisco, California, specializes in the development and commercialization of next-generation geothermal power technology. The company focuses on owning, developing, and operating geothermal assets to generate clean, carbon-free energy in new locations. By leveraging innovations in geoscience, Fervo Energy aims to accelerate the transition to a sustainable energy future, positioning itself as a key player in the evolution of the electric grid. Its proprietary technology serves as a dispatchable foundation for achieving a fully clean energy system, enabling clients to enhance productivity and scalability in energy production.

Enzinc is an advanced battery developer focused on creating rechargeable zinc-air batteries that utilize innovative NRL technology. These batteries are designed to combine the energy density of lithium-ion batteries with the cost-effectiveness of lead-acid systems, while also prioritizing safety. By employing zinc as a primary material, Enzinc's products promise not only high energy density but also a cleaner and safer energy source suitable for various applications. The company emphasizes the advantages of using zinc, a plentiful and recyclable metal, which offers performance that is equivalent to or superior to that of lithium-ion alternatives, thereby advancing the industry towards more sustainable energy solutions.

Kaleidoscope is a company that specializes in the design, administration, and hosting of branded scholarship and grant programs through a cloud-based marketplace. Founded in 2016 by Gregory Dehn and headquartered in Minneapolis, Minnesota, Kaleidoscope connects scholarship funders with students, facilitating a seamless marketplace that matches qualified candidates with personalized scholarship opportunities. The company’s platform is tailored to support organizations and advocates in their efforts to fund the next generation of leaders, artists, and entrepreneurs, emphasizing low administrative costs and student choice. By providing innovative and impactful program design, Kaleidoscope aims to enhance access to educational funding and streamline the scholarship management process.

Koya Medical, Inc. is a healthcare company based in Oakland, California, founded in 2018. The company specializes in developing innovative wearable therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. Koya Medical's technology offers active compression therapy that enhances mobility and personalized care, addressing limitations commonly associated with traditional compression methods. Its sensor-based closed-loop system provides patient-specific patterned compression, enabling healthcare providers to effectively manage conditions like chronic edema and chronic venous insufficiency. Through its breakthrough treatments, Koya Medical seeks to transform the standard of care for individuals affected by these debilitating conditions.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, founded in 2016. The company specializes in developing innovative biotherapeutics and self-regulating drugs that provide therapeutic activity in a context-dependent manner. Their core technology involves designing allosterically-regulated proteins that can detect specific biomarkers and respond accordingly, activating therapeutic functions only when and where needed. This approach aims to enhance drug safety and efficacy by reducing systemic toxicity while maintaining therapeutic effectiveness. Currently, Good Therapeutics is primarily focused on applications within immuno-oncology, aiming to create safer and more effective treatment options that optimize patient outcomes.

Claros Technologies is an advanced materials company that develops safe and sustainable products with zero toxic waste. It strives to lead the industry towards a holistic approach to materials design and innovation. It was founded in 2018 and is based in St Paul, Minnesota.

Source is a company that specializes in the development and manufacturing of solar-powered hydro panels that extract drinkable water from the atmosphere. Founded in 2014 and based in Scottsdale, Arizona, Source employs advanced materials science to create devices capable of producing pure, mineralized water even in arid conditions. Their technology is designed for a variety of applications, including industrial, commercial, residential, and community use, allowing individuals and businesses to access clean water virtually anywhere.

Amplyx Pharmaceuticals, Inc. is a small molecule drug development company focused on creating innovative therapies for debilitating and life-threatening diseases, particularly those affecting individuals with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in the development of oral and injectable anti-infective drugs, including antifungal agents designed to treat invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by incorporating a second small molecule. This strategy aims to provide effective treatment options for patients undergoing chemotherapy and other immunosuppressive therapies, ensuring they receive appropriate care both during hospitalization and after discharge.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, founded in 2016. The company specializes in developing innovative biotherapeutics and self-regulating drugs that provide therapeutic activity in a context-dependent manner. Their core technology involves designing allosterically-regulated proteins that can detect specific biomarkers and respond accordingly, activating therapeutic functions only when and where needed. This approach aims to enhance drug safety and efficacy by reducing systemic toxicity while maintaining therapeutic effectiveness. Currently, Good Therapeutics is primarily focused on applications within immuno-oncology, aiming to create safer and more effective treatment options that optimize patient outcomes.

Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.

Smart Wires is an electrical and electronics company founded in 2010 and headquartered in San Francisco, California. It specializes in grid optimization solutions, particularly for medium and high voltage electricity transmission grids. The company develops and manufactures modular power flow control technology devices designed to manage and direct power flow within high electric transmission systems. By utilizing advanced power electronics hardware and software, Smart Wires enhances and optimizes grid capacity, addressing challenges such as transmission reliability and congestion management in the evolving energy landscape.

InterVene, Inc. is a medical device company based in South San Francisco, California, specializing in innovative treatments for chronic venous insufficiency (CVI), particularly focusing on deep vein valve failure. Incorporated in 2011, the company develops catheter-based therapies aimed at restoring valvular competency in patients experiencing severe venous conditions. Its flagship product, the BlueLeaf™ Endovenous Valve Formation System, provides a non-implantable solution that enables physicians to create new vein valves using the patient's own vein wall tissue. By offering minimally invasive therapies, InterVene seeks to improve patient outcomes related to venous stasis ulcers and other symptoms associated with chronic venous disease.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, founded in 2016. The company specializes in developing innovative biotherapeutics and self-regulating drugs that provide therapeutic activity in a context-dependent manner. Their core technology involves designing allosterically-regulated proteins that can detect specific biomarkers and respond accordingly, activating therapeutic functions only when and where needed. This approach aims to enhance drug safety and efficacy by reducing systemic toxicity while maintaining therapeutic effectiveness. Currently, Good Therapeutics is primarily focused on applications within immuno-oncology, aiming to create safer and more effective treatment options that optimize patient outcomes.

Allakos Inc. is a clinical-stage biopharmaceutical company founded in 2012 and headquartered in Redwood City, California. The company focuses on developing antibody-based therapeutics aimed at treating diseases associated with dysregulation of the T-helper type 2 immune response, which plays a crucial role in various allergic and inflammatory conditions. Its lead product, antolimab (AK002), is being investigated for the treatment of eosinophilic gastritis, eosinophilic gastroenteritis, chronic urticaria, indolent systemic mastocytosis, and severe allergic conjunctivitis. Additionally, Allakos is developing AK006, an antibody that targets the Siglec-6 receptor on mast cells, designed to activate the receptor's inhibitory function and reduce mast cell activation. Through these innovative therapies, Allakos aims to address the underlying mechanisms of diseases characterized by excessive inflammatory responses.

Fishpeople Seafood is a food production company founded in 2012 and headquartered in Portland, Oregon. The company specializes in providing sustainable seafood products to grocery retailers, aiming to disrupt the traditional seafood industry with innovative offerings. Fishpeople Seafood's product range includes wild American salmon, tuna, crab, and cod, all sourced sustainably. By focusing on authentic fish meat alternatives, Fishpeople Seafood enables consumers to embrace healthier and more environmentally responsible eating habits. The company is recognized for its rapid growth and commitment to sustainability in the seafood market.