The 49th State Angel Fund is a government-backed venture capital organization in Anchorage, Alaska, established in 2012 under the US Treasury State Small Business Credit Initiative program. It provides capital to high-growth Alaska-based businesses, directly and indirectly, and collaborates with partner funds to offer matching private investment. Its management team supplies entrepreneurial and managerial expertise to portfolio companies, with the aim of promoting entrepreneurship, innovation, and job creation for the Anchorage community.

PLG Ventures is an early-stage venture capital firm founded in 2015 and headquartered in Santa Monica, California. It specializes in pre-seed and seed investments for technology-enabled startups, primarily focusing on Southern California. The firm provides hands-on support to founding teams, helping them develop leadership skills and emotional intelligence while setting up scalable growth foundations.

Founded in 2014, Kirenaga Partners is a venture capital firm based in Winter Park, Florida. It specializes in early-stage investments in transformative technologies addressing major social issues such as clean water and fresh food. The firm focuses on companies with less than $25 million in annual revenue, providing initial funding of $1-3 million and offering operational support to de-risk and scale portfolio companies.

Founded in 2000, Lux Capital is a venture capital firm based in New York and Silicon Valley. It manages over $5 billion in assets, focusing on seed to growth investments at the intersection of technology and sciences. Lux actively supports entrepreneurs building successful businesses in high-growth sectors such as biochemistry, material science, electronics, infrastructure, aerospace, genomics, synthetic biology, and robotics.

Blue Venture Fund is the corporate venture capital arm of the BlueCross and BlueShield Association, based in Chicago. It operates as a strategic investor in healthcare, backing emerging companies in healthcare technology, healthcare services, and clinical sciences. The organization targets innovations that improve quality of care, enhance patient experience, and reduce costs, aligning with the needs of BCBS member companies and their policyholders. By funding early to growth-stage ventures, it supports the adoption of new solutions within the healthcare system and complements BCBS efforts to advance value-based care.

Founded in 2015, 1517 Fund is a venture capital firm based in Telluride, Colorado. It supports early-stage technology startups with pre-seed and seed funding, focusing on individuals passionate about creating new technologies outside traditional academic paths.

Base Ventures is a seed-stage venture capital firm based in Berkeley, California, founded in 2016. It concentrates on early investments in technology companies across sectors such as B2B software, information technology, retail, clean technology, advanced manufacturing, construction technology, industrials, infrastructure, manufacturing, SaaS, supply chain, and marketing technology. The firm supports startups through initial rounds and collaborates with founders to accelerate growth and product development. Its portfolio includes MOS, Blavity, Space Perspective, Genies, 6Sense, and AngelList, among others, with notable exits including Olly Nutrition and PlanGrid. Base Ventures aims to back companies that combine strong technology with scalable business models and global potential.

Prime Movers Lab is a Wyoming-based venture capital firm founded in 2018 and headquartered in Jackson. It targets early-stage investments in deep-technology startups spanning energy, transportation, infrastructure, manufacturing, and agriculture, as well as adjacent areas such as human augmentation, autonomous systems, aerospace, drones, water, quantum computing, advanced materials, clean energy, and new space technology. The firm also backs health innovation and sustainable food initiatives. It makes equity investments in a range of roughly $0.25 million to $5 million and does not take board seats, lead rounds, co-invest, or seek controlling stakes, nor does it invest in publicly listed securities.

FirstMark Capital is an early-stage venture capital firm based in New York City. Founded in 2008 in a spin-out from Pequot Capital Management's venture business, the firm partners with exceptional founders to build iconic technology companies across enterprise and consumer sectors. It has backed notable companies such as Pinterest, Shopify, DraftKings, Discord, Airbnb, StubHub, Riot Games, and InVision, among others, reflecting a strong presence in the New York venture ecosystem.

Grok Ventures is a venture capital firm founded in 2008 and located in Surry Hills, Australia. The firm focuses on investing in technology-enabled businesses with a particular emphasis on climate-related companies and infrastructure. Grok Ventures aims to support innovative solutions that address environmental challenges while fostering sustainable growth in the technology sector. Through its investments, the firm seeks to contribute positively to the climate landscape on a global scale.

Nucleus Capital is a Berlin-based venture capital firm founded in 2020 that focuses on supporting purpose-driven entrepreneurs. The firm is dedicated to addressing global challenges related to human and planetary health through entrepreneurial innovation. Nucleus Capital specializes in pre-seed and seed-stage investments, targeting companies in the fields of synthetic and computational biology, food technology, and climate technology. By partnering with founders at the early stages of their ventures, Nucleus Capital aims to foster innovative solutions that contribute to a sustainable future.

Nomadic Venture Partners is a Denver-based venture capital firm established in 2021 that funds early-stage companies in digital and light hardware solutions across the United States and Canada, with a focus on climate technology and decarbonization in natural resources, manufacturing, and transportation sectors.

Overture VC is a venture capital firm founded in 2021 and headquartered in Los Angeles, California. It focuses on early‑stage climate‑technology companies, providing capital and expertise to help them navigate government and regulatory challenges. The firm supports visionaries working toward a sustainable future.

Alyeska Venture Management, founded in 2014 and based in Anchorage, Alaska, is a venture capital firm that focuses on supporting early-stage entrepreneurs within the region. The firm manages the Alaska Accelerator Fund, which aims to accelerate the growth of startups by leveraging the expertise of experienced managers, advisors, and angel investors. Through its initiatives, Alyeska Venture Management seeks to add value to emerging companies and foster a vibrant entrepreneurial ecosystem in Alaska.

Founded in 1987, Canaan Partners is a global venture capital firm based in Menlo Park, California. With over $5 billion under management, the firm invests in early-stage technology and healthcare companies worldwide.

SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.

Established in 2020 and headquartered in Arlington, Virginia, E2MC is a specialized venture capital firm dedicated to investing in the space sector.

SpaceFund is a venture capital firm based in Houston, Texas, focused on practical, high-growth startups in space markets that enable the space revolution. It prioritizes space technology companies rather than traditional aerospace, satellite swarms, rockets, or weapons, though it may invest in space transportation. The firm emphasizes active, hands-on support and nurture across all stages of development, from seed to later rounds. It backs ventures in consumer products and services related to space and seeks bold, nimble teams guided by integrity, humility, and pragmatism to drive meaningful progress in the space economy.

Wakestream Ventures is a venture capital firm based in Grand Rapids, Michigan, specializing in seed and early-stage investments in technology companies. Established in 2012, the firm focuses on businesses at the intersection of hardware and software, as well as e-commerce, primarily within the United States but with a special emphasis on Michigan. Wakestream Ventures typically invests between $100,000 and $300,000 in initial funding, with the potential for follow-on investments totaling up to $1.5 million across subsequent rounds. To qualify for investment, companies must be registered as Michigan LLCs and provide progress updates within 60 to 90 days. The firm does not invest in non-profit organizations and requires investee companies to engage with its team in Grand Rapids, utilizing the region's resources for growth. Additionally, Wakestream Ventures retains the right of first refusal for future outside investments, converting this right into equity under certain conditions.

RRE Ventures is a New York-based venture capital firm founded in 1994 that focuses on early-stage technology and financial services companies. It typically invests in seed and Series A rounds, with participation in Series B in select cases, and supports a broad portfolio across sectors including artificial intelligence, climate, consumer tech, cryptocurrency, enterprise software, fintech, healthcare, media, real estate, robotics, and space. The firm pursues opportunities across the United States and Canada and maintains a registered investment adviser status. By backing innovative technology solutions and scalable business models, RRE Ventures aims to help early-stage companies grow to broader markets.

Founded in 2013, Montage Ventures is a venture capital firm based in Menlo Park, California. The firm invests in early-stage startups across various sectors including financial services, commerce, and health, with a focus on innovative ideas and platforms.

Founded in 2017, GingerBread Capital is a venture capital firm based in Menlo Park, California. It invests in women-led businesses, providing them with access to knowledge, networks, and capital to build and scale successful enterprises.

Factor[e] Ventures is an impact venture builder and investment firm that supports early-stage companies in mobility, agriculture, energy and water. Based in Fort Collins, Colorado, it operates across emerging and frontier markets with a focus on Sub-Saharan Africa, backing market-driven solutions that advance sustainable development. The organization connects philanthropic and commercial investors pursuing decarbonized growth, aiming to turn disruptive ideas into scalable businesses addressing energy, agriculture, mobility and waste challenges in fast-growing regions.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Tiger Global Management is a New York based investment firm that manages public and private market strategies to pursue technology-driven growth opportunities worldwide. Founded in 2001 by Charles (Chase) Coleman, the firm invests in leading global companies across various industries, with a particular emphasis on technology-enabled growth. In public markets it employs long/short and growth strategies, while in private markets it targets opportunities from early to late stage. The firm operates globally, including the United States, China, India, Latin America, and Eastern Europe, and works with portfolio companies across their lifecycle to drive long-term value.

Founded in 2014, Gaingels is a venture investment syndicate dedicated to supporting the LGBT+ community. It invests globally in companies led by LGBT+ founders or C-suite executives at all stages of growth, focusing on inclusivity and positive social change.

Aligned Climate Capital is a New York-based venture capital firm founded in 2019 that focuses on decarbonizing the global economy. It invests in people, companies, and real assets that support clean energy, efficient transportation, green real estate, and sustainable natural resources, seeking strong financial returns alongside meaningful environmental and social impact. The firm operates as an investment adviser and concentrates on opportunities in low-carbon and sustainable assets across infrastructure and related sectors.

Founded in 2011, Slow Ventures is a San Francisco-based early-stage venture capital firm. It invests in innovative companies operating at the intersection of technology, science, society, and culture across various sectors such as software, biotechnology, e-commerce, fintech, and more.

Glynn Capital Management is a Menlo Park-based investment firm with an office in San Francisco that focuses on technology-oriented investments across private and public markets. Founded in 1974, it pursues long-term ownership in a small number of companies with strong management teams, sustainable business models, and meaningful growth potential. The firm concentrates on information technology, artificial intelligence, big data, cybersecurity, software, and fintech sectors, targeting opportunities in both private and public technology companies at early and growth stages. It emphasizes enduring relationships with portfolio companies and value creation through disciplined capital allocation and strategic support. The firm operates as an investment adviser, aligning its interests with those of its clients and portfolio companies.

SemperVirens Venture Capital is an early-stage venture capital investment firm founded in 2018 and based in San Mateo, California. The firm focuses on investing in companies within the workforce technology, healthcare technology, and financial technology sectors, aiming to address the needs of employers. SemperVirens is recognized for its team's deep industry experience, strong relationships, and valuable insights, which support its investment strategy and foster the growth of innovative companies in these domains. As a Registered Investment Adviser, SemperVirens is committed to guiding its portfolio companies toward success in a rapidly evolving market.

Charge Ventures is a venture capital firm founded in 2015 and based in Brooklyn, New York. The firm focuses on seed and early-stage investments in a variety of sectors, including artificial intelligence, machine learning, augmented reality, virtual reality, blockchain, mobile applications, marketplaces, logistics, software as a service, direct-to-consumer healthcare, and the future of work. While it invests across the United States, Charge Ventures has a particular emphasis on opportunities in New York City and other major metropolitan areas such as Chicago, Atlanta, Boston, San Diego, and Miami.

Evolution Ventures engages in investments and strategic partnerships to build a global platform that brings together leaders, investors, and corporates.

Spark Capital is a venture capital firm founded in 2005 and based in San Francisco with offices in Boston and New York. It invests in startups across the United States, spanning early-stage to growth opportunities, focusing on software, internet, media, consumer products and services, fintech, and information technology. The firm backs companies across sectors such as software-as-a-service, digital media, online platforms, and technology-driven consumer products, often supporting ventures at the intersection of entertainment and technology, e-commerce, and education technology. It typically makes investments from formative rounds up to larger growth rounds, and seeks to take a board seat in portfolio companies to help guide strategy and growth. Notable investments include Twitter, Discord, Anthropic, Cruise, Niantic, Oculus, Warby Parker, and Tumblr, illustrating a history of backing influential products and teams.

Trinity Capital is a lending firm that provides debt-based financing to growth-stage and venture-backed companies, including venture debt, revolving lines, senior and subordinated debt, and equipment financing. Headquartered in Phoenix, Arizona, it was founded in 2008 and collaborates with venture capital firms, technology banks, and portfolio companies to tailor financing solutions that help startups preserve equity while obtaining capital. The firm focuses on technology-driven and knowledge-based sectors, including healthcare, information technology, software as a service, financial services, consumer products, manufacturing, energy, cleantech, and nanotechnology, and supports growth, early-stage to later-stage ventures, buyouts, and acquisitions. Trinity Capital aims to partner with venture-backed startups seeking flexible capital to fuel growth, scale operations, or navigate strategic transactions.

Polychain Capital is a venture capital firm based in San Francisco that invests in blockchain technologies and blockchain assets. It supports protocols and companies in the blockchain space and seeks to advance the global adoption of cryptocurrencies. The firm aims to deliver attractive returns for its investors through actively managed investments across digital assets and blockchain projects.

Manhattan Venture Partners is a New York-based venture capital and private equity firm established in 2014, specializing in secondary investments in late-stage private technology companies and pre-IPO firms. The company has played a pivotal role in the institutionalization of the secondary market for venture-backed entities and has facilitated over $10 billion in primary and secondary investments. It stands out through its research capabilities, particularly via Manhattan Venture Research, which produces unbiased reports on private technology companies, addressing the informational challenges prevalent in the venture capital space. The firm provides a comprehensive suite of services, including direct and managed secondary investment opportunities, advisory services, and transaction facilitation, ensuring efficient and compliant processes. Manhattan Venture Partners targets well-capitalized companies with strong growth potential, primarily in sectors such as media, financial services, and information technology, leveraging its extensive experience to streamline transactions for private companies and their stakeholders.

Founded in Tel Aviv, Israel, iAngels is a women-led venture capital firm recognized for its active investment in Israeli startups. It operates a global crowdfunding platform connecting investors with technology startup opportunities worldwide. The firm invests across various sectors including software, healthcare, fintech, and consumer products.

Goodwater Capital is a California-based venture capital firm founded in 2014 that targets early-stage investments in consumer technology and related sectors, including housing, financial services, consumer products and services, healthcare, food, transportation, education, and entertainment. It backs exceptional entrepreneurs who create products and platforms that consumers love, with a focus on solving pressing problems and shaping the culture and global economy. Through its investments, Goodwater aims to enable startups capable of delivering broad, measurable improvements in billions of lives, reflecting a commitment to long-term positive impact.

Shenzhen Guozhong Venture Capital Management Co., Ltd. was established on December 21, 2015, and is based in Shenzhen, China. The firm manages the first entity fund of the Small Medium Enterprises Development Fund, which has a total size of 6 billion Yuan. With a registered capital of 100 million Yuan, its ownership is split between the Shenzhen Venture Capital Group (49%) and the management team of the Small Medium Enterprises Development Fund (51%). Guozhong Venture Capital focuses on investing in innovative technology, biomedical, healthcare, and TMT (technology, media, and telecommunications) sectors, aiming to support the growth of small and medium-sized enterprises in these dynamic fields.

Zero2IPO Group is an integrated service provider in China's venture capital and private equity sector. Headquartered in Beijing with offices in Shanghai, Shenzhen, Hong Kong and Silicon Valley, it operates a network-focused platform that sources deals, conducts market research, and provides financial advisory services. Through its subsidiaries, including venture investment arms, the group invests and manages funds to back high-potential, high-growth Chinese enterprises, co-investing with active venture funds and leading or co-leading early-stage startups. Its services encompass investment forums, training programs, and advisory offerings that connect entrepreneurs with investors, helping portfolio companies scale across sectors such as Internet, mobile applications, digital media, healthcare, and green technologies. Zero2IPO Group positions itself as a value-add partner in the venture capital ecosystem, leveraging its extensive China network to identify opportunities and support value creation.

Matrix is a San Francisco based venture capital firm founded in 1977 that backs early-stage companies across AI, B2B, consumer, fintech, health tech, and infrastructure. It works with product teams from idea through Series A, offering hands-on support and strategic guidance to help portfolio companies reach scale. The team comprises former founders and operators who bring practical insight to building startups. Matrix operates globally, including Matrix Partners China, which builds long-term relationships with entrepreneurs in China and abroad and invests across sectors and stages. Over its history, Matrix has backed companies that progressed to IPOs or acquisitions, reflecting a focus on durable growth and long-term value creation through close founder collaboration and a global network.

Founded in 2004 and based in Palo Alto, California, Uncork Capital is a venture capital firm focusing on seed-stage investments in SaaS, consumer goods, healthcare, and technology companies across the United States. The firm invests out of two funds: a $200M Seed fund and a $200M Opportunity fund for larger investments in mature portfolio companies.

Insight Partners is a global private equity and venture capital firm founded in 1995 that acts as a software investor, partnering with growth-stage technology and software companies. The firm concentrates on Fintech, Cybersecurity, AI/ML, DevOps, and Healthcare, providing capital and hands-on support to help management teams scale. Headquartered in New York City with offices in London, Tel Aviv, and Palo Alto, Insight Partners has more than $75 billion in assets under management, has invested in over 750 companies worldwide, and more than 55 portfolio companies have reached an IPO.

LightShed Ventures is an early-stage venture capital firm based in New York, founded in 2021. It invests in startups across technology, media, telecom, and consumer sectors, with emphasis on B2B, B2C, and information technology companies, and provides capital and strategic guidance to help founders scale their businesses.

Explorer 1 Fund is a venture capital firm based in Los Angeles, California, founded in 2021. The firm focuses on investing in companies within the emerging space economy, targeting innovative ventures that operate in the space sector. Through its investments, Explorer 1 Fund aims to support the growth and development of businesses that contribute to advancements in space technology and exploration.

Network Ventures is a Chicago-based venture capital firm founded in 2016 that focuses on providing funding to seed stage companies. The firm primarily invests in businesses within the internet and technology sectors, aiming to support early-stage companies as they develop and grow. By concentrating on these industries, Network Ventures seeks to foster innovation and facilitate the success of emerging entrepreneurs.

Kosmos Ventures is a prominent venture capital firm based in Perth, Australia, established in 2017. The company specializes in blockchain-based assets and has been an early supporter of notable projects like Algorand, Solana, Polkadot, and Oasis. Kosmos Ventures focuses on investments in the blockchain, infrastructure, cryptocurrency, and digital asset sectors, prioritizing large infrastructure initiatives while also backing successful decentralized finance (DeFi) and gaming finance (GameFi) projects. The firm maintains active involvement in major Layer 1 networks and contributes to their growth through validator staking in collaboration with partners.

Founded in 2013 by Drexel University students Yakir Gola and Rafael Ilishayev, Gopuff is a pioneering instant commerce platform that delivers essential products directly to consumers' doorsteps. Its extensive product range includes over-the-counter medicine, baby food, cleaning supplies, snacks, beverages, and select alcoholic drinks, ensuring customers can satisfy their needs and cravings promptly.

Founded in 2016, Climate Impact Capital is an impact investment firm based in Houston, Texas. It focuses on early-stage technology companies addressing climate change through innovations in energy, food, and water solutions.

Founded in Seattle, Washington in 2018, SeaChange is a venture capital firm focused on investing in early-stage startups across the Pacific Northwest and British Columbia regions.