The 49th State Angel Fund is a government-backed venture capital organization in Anchorage, Alaska, established in 2012 under the US Treasury State Small Business Credit Initiative program. It provides capital to high-growth Alaska-based businesses, directly and indirectly, and collaborates with partner funds to offer matching private investment. Its management team supplies entrepreneurial and managerial expertise to portfolio companies, with the aim of promoting entrepreneurship, innovation, and job creation for the Anchorage community.

PLG Ventures is an early-stage venture capital firm founded in 2015 and headquartered in Santa Monica, California. It specializes in pre-seed and seed investments for technology-enabled startups, primarily focusing on Southern California. The firm provides hands-on support to founding teams, helping them develop leadership skills and emotional intelligence while setting up scalable growth foundations.

Kirenaga Partners is a Florida-based venture capital firm that backs early-stage, transformative technologies with potential for societal impact. Founded in 2014 and based in Winter Park and Orlando, the firm targets lower middle market companies across sectors such as advanced manufacturing, ag-tech, artificial intelligence and machine learning, clean technology, education technology, robotics, drones, life and material sciences, and space technology. Typical investments range from 1 to 3 million, providing 18 to 24 months of runway, and the firm supports portfolio companies with hands-on operating expertise and a national professional network to de-risk and accelerate growth. The focus is on companies with less than about 25 million in annual revenue, aligning with an early-stage, growth-oriented strategy.

Founded in 2000, Lux Capital is a venture capital firm based in New York and Silicon Valley. It manages over $5 billion in assets, focusing on seed to growth investments at the intersection of technology and sciences. Lux actively supports entrepreneurs building successful businesses in high-growth sectors such as biochemistry, material science, electronics, infrastructure, aerospace, genomics, synthetic biology, and robotics.

The Blue Venture Fund is the corporate venture capital arm of the BlueCross BlueShield Association, based in Chicago. It invests in healthcare technology, healthcare services, and clinical sciences companies with the potential to improve care quality, patient experience, and cost efficiency, and seeks opportunities that align with the needs of BCBS member companies and their policyholders to foster innovation within the healthcare system.

Grok Ventures is a venture capital firm founded in 2008 and located in Surry Hills, Australia. The firm focuses on investing in technology-enabled businesses with a particular emphasis on climate-related companies and infrastructure. Grok Ventures aims to support innovative solutions that address environmental challenges while fostering sustainable growth in the technology sector. Through its investments, the firm seeks to contribute positively to the climate landscape on a global scale.

Overture VC is a venture capital firm based in Los Angeles, founded in 2021, that concentrates on early-stage climate-tech startups. It provides investment capital and practical government strategies to help portfolio companies navigate the regulatory landscape and access public sector support. By assisting founders in winning government support and addressing regulatory complexity, Overture VC aims to accelerate the development and deployment of climate solutions. The firm focuses on ventures that pursue a sustainable future and seeks to empower founders to scale their innovations by aligning policy, funding, and market pathways.

Nucleus Capital is a Berlin-based venture capital firm founded in 2020 that focuses on supporting purpose-driven entrepreneurs. The firm is dedicated to addressing global challenges related to human and planetary health through entrepreneurial innovation. Nucleus Capital specializes in pre-seed and seed-stage investments, targeting companies in the fields of synthetic and computational biology, food technology, and climate technology. By partnering with founders at the early stages of their ventures, Nucleus Capital aims to foster innovative solutions that contribute to a sustainable future.

Nomadic Venture Partners is a Denver-based venture capital firm established in 2021 that funds early-stage companies in digital and light hardware solutions across the United States and Canada, with a focus on climate technology and decarbonization in natural resources, manufacturing, and transportation sectors.

Prime Movers Lab is a Wyoming-based venture capital firm founded in 2018 and headquartered in Jackson. It targets early-stage investments in deep-technology startups spanning energy, transportation, infrastructure, manufacturing, and agriculture, as well as adjacent areas such as human augmentation, autonomous systems, aerospace, drones, water, quantum computing, advanced materials, clean energy, and new space technology. The firm also backs health innovation and sustainable food initiatives. It makes equity investments in a range of roughly $0.25 million to $5 million and does not take board seats, lead rounds, co-invest, or seek controlling stakes, nor does it invest in publicly listed securities.

Founded in 2015, 1517 Fund is a venture capital firm based in Telluride, Colorado. It supports early-stage technology startups with pre-seed and seed funding, focusing on individuals passionate about creating new technologies outside traditional academic paths.

Base Ventures is a seed-stage venture capital firm based in Berkeley, California, founded in 2016. It concentrates on early investments in technology companies across sectors such as B2B software, information technology, retail, clean technology, advanced manufacturing, construction technology, industrials, infrastructure, manufacturing, SaaS, supply chain, and marketing technology. The firm supports startups through initial rounds and collaborates with founders to accelerate growth and product development. Its portfolio includes MOS, Blavity, Space Perspective, Genies, 6Sense, and AngelList, among others, with notable exits including Olly Nutrition and PlanGrid. Base Ventures aims to back companies that combine strong technology with scalable business models and global potential.

FirstMark Capital is a New York City-based venture capital firm founded in 2008 that backs early-stage technology companies. It collaborates with exceptional founders to build iconic enterprise and consumer software and platform companies and has supported notable businesses such as Pinterest, Shopify, DraftKings, Discord, Airbnb, StubHub, Riot Games, and InVision.

SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.

Alyeska Venture Management, founded in 2014 and based in Anchorage, Alaska, is a venture capital firm that focuses on supporting early-stage entrepreneurs within the region. The firm manages the Alaska Accelerator Fund, which aims to accelerate the growth of startups by leveraging the expertise of experienced managers, advisors, and angel investors. Through its initiatives, Alyeska Venture Management seeks to add value to emerging companies and foster a vibrant entrepreneurial ecosystem in Alaska.

Canaan Partners is a San Francisco-based venture capital firm founded in 1987 that operates globally with offices in Israel and India. It focuses on early-stage investments in technology and healthcare, including software, fintech, enterprise/cloud, marketplaces, digital health, biopharma, and medtech, and it has a history of backing startups that achieve exits.

SpaceFund is a venture capital firm based in Houston, Texas, focused on practical, high-growth startups in space markets that enable the space revolution. It prioritizes space technology companies rather than traditional aerospace, satellite swarms, rockets, or weapons, though it may invest in space transportation. The firm emphasizes active, hands-on support and nurture across all stages of development, from seed to later rounds. It backs ventures in consumer products and services related to space and seeks bold, nimble teams guided by integrity, humility, and pragmatism to drive meaningful progress in the space economy.

Established in 2020 and headquartered in Arlington, Virginia, E2MC is a specialized venture capital firm dedicated to investing in the space sector.

RRE Ventures is a New York-based venture capital firm that backs early-stage technology companies, primarily in seed and Series A rounds, across a broad range of sectors. Founded in 1994, the firm looks for innovative, scalable business models and supports companies aiming to leverage technology to create value. Its investment scope spans artificial intelligence, climate, consumer technology, cryptocurrency, enterprise software and services, financial technology, healthcare, media, real estate, robotics, and space, with activity across the United States and Canada.

Wakestream Ventures is a Grand Rapids, Michigan-based venture capital firm that funds early-stage technology companies, with a focus on the convergence of hardware and software and internet-enabled physical products such as IoT devices. It invests in seed and early-stage ventures in the United States, particularly those leveraging hardware design, industrial design, and manufacturing. Typical initial investments range in the low hundreds of thousands, with follow-ons up to about $1.5 million cumulatively.

Montage Ventures is a Menlo Park, California-based venture capital firm founded in 2013. It provides seed and growth capital to technology-enabled startups across financial services, consumer goods, e-commerce, marketplaces, software, and healthcare. The firm targets early and growth-stage opportunities in the United States, Canada, South America, Southeast Asia, and other parts of the Americas, supporting innovative platforms and experiences that drive transformative change in finance, commerce, and health sectors.

GingerBread Capital is a California-based family office investment firm that makes early- and later-stage growth investments in women-founded and women-led technology-enabled companies, providing capital along with knowledge and networks to help these businesses grow and scale.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Factor[e] Ventures is an impact venture builder and investment firm that supports early-stage companies in mobility, agriculture, energy and water. Based in Fort Collins, Colorado, it operates across emerging and frontier markets with a focus on Sub-Saharan Africa, backing market-driven solutions that advance sustainable development. The organization connects philanthropic and commercial investors pursuing decarbonized growth, aiming to turn disruptive ideas into scalable businesses addressing energy, agriculture, mobility and waste challenges in fast-growing regions.

Tiger Global Management is an investment firm founded in 2001 by Charles (Chase) Coleman. It allocates capital across public and private markets worldwide, with a focus on technology-enabled growth opportunities. The firm pursues public equity strategies, including long/short and growth investments, and private equity across early- to late-stage companies in multiple industries, seeking high-quality growth opportunities and guiding portfolio companies through their lifecycle.

Gaingels is a venture investment organization focused on LGBTQ+-founded and led companies and their allies, investing across stages from pre-seed to pre-IPO and maintaining a global portfolio. Founded in 2014 and based in New York, it operates as a syndicate with more than 130 portfolio companies and around $70 million deployed. The organization supports inclusive leadership by backing ventures that promote diverse C-suite and board representation and actively assists portfolio companies in recruiting diverse executive talent. It also fosters a global community of industry leaders, investors, operators, and entrepreneurs who pursue positive social change through business and successful investments.

Aligned Climate Capital is a New York-based venture capital firm founded in 2019 that focuses on decarbonizing the global economy. It invests in people, companies, and real assets that support clean energy, efficient transportation, green real estate, and sustainable natural resources, seeking strong financial returns alongside meaningful environmental and social impact. The firm operates as an investment adviser and concentrates on opportunities in low-carbon and sustainable assets across infrastructure and related sectors.

Founded in 2011, Slow Ventures is a San Francisco-based early-stage venture capital firm. It invests in innovative companies operating at the intersection of technology, science, society, and culture across various sectors such as software, biotechnology, e-commerce, fintech, and more.

SemperVirens Venture Capital is an early-stage venture capital investment firm founded in 2018 and based in San Mateo, California. The firm focuses on investing in companies within the workforce technology, healthcare technology, and financial technology sectors, aiming to address the needs of employers. SemperVirens is recognized for its team's deep industry experience, strong relationships, and valuable insights, which support its investment strategy and foster the growth of innovative companies in these domains. As a Registered Investment Adviser, SemperVirens is committed to guiding its portfolio companies toward success in a rapidly evolving market.

Charge Ventures is a venture capital firm founded in 2015 and based in Brooklyn, New York. The firm focuses on seed and early-stage investments in a variety of sectors, including artificial intelligence, machine learning, augmented reality, virtual reality, blockchain, mobile applications, marketplaces, logistics, software as a service, direct-to-consumer healthcare, and the future of work. While it invests across the United States, Charge Ventures has a particular emphasis on opportunities in New York City and other major metropolitan areas such as Chicago, Atlanta, Boston, San Diego, and Miami.

Evolution Ventures engages in investments and strategic partnerships to build a global platform that brings together leaders, investors, and corporates.

Glynn Capital Management is a Menlo Park-based investment firm with an office in San Francisco that focuses on technology-oriented investments across private and public markets. Founded in 1974, it pursues long-term ownership in a small number of companies with strong management teams, sustainable business models, and meaningful growth potential. The firm concentrates on information technology, artificial intelligence, big data, cybersecurity, software, and fintech sectors, targeting opportunities in both private and public technology companies at early and growth stages. It emphasizes enduring relationships with portfolio companies and value creation through disciplined capital allocation and strategic support. The firm operates as an investment adviser, aligning its interests with those of its clients and portfolio companies.

Spark Capital is a venture capital firm founded in 2005 and based in San Francisco with offices in Boston and New York. It invests in startups across the United States, spanning early-stage to growth opportunities, focusing on software, internet, media, consumer products and services, fintech, and information technology. The firm backs companies across sectors such as software-as-a-service, digital media, online platforms, and technology-driven consumer products, often supporting ventures at the intersection of entertainment and technology, e-commerce, and education technology. It typically makes investments from formative rounds up to larger growth rounds, and seeks to take a board seat in portfolio companies to help guide strategy and growth. Notable investments include Twitter, Discord, Anthropic, Cruise, Niantic, Oculus, Warby Parker, and Tumblr, illustrating a history of backing influential products and teams.

Polychain Capital is a venture capital firm based in San Francisco, founded in 2016, that invests in blockchain technologies, protocols, and companies to advance global adoption of cryptocurrencies. The firm supports the development of the blockchain ecosystem and provides capital to projects across the space. It operates as a registered investment adviser (RIA).

Trinity Capital is a lending firm that provides debt-based financing to growth-stage and venture-backed companies, including venture debt, revolving lines, senior and subordinated debt, and equipment financing. Headquartered in Phoenix, Arizona, it was founded in 2008 and collaborates with venture capital firms, technology banks, and portfolio companies to tailor financing solutions that help startups preserve equity while obtaining capital. The firm focuses on technology-driven and knowledge-based sectors, including healthcare, information technology, software as a service, financial services, consumer products, manufacturing, energy, cleantech, and nanotechnology, and supports growth, early-stage to later-stage ventures, buyouts, and acquisitions. Trinity Capital aims to partner with venture-backed startups seeking flexible capital to fuel growth, scale operations, or navigate strategic transactions.

Manhattan Venture Partners is a New York-based venture capital and private equity firm established in 2014, specializing in secondary investments in late-stage private technology companies and pre-IPO firms. The company has played a pivotal role in the institutionalization of the secondary market for venture-backed entities and has facilitated over $10 billion in primary and secondary investments. It stands out through its research capabilities, particularly via Manhattan Venture Research, which produces unbiased reports on private technology companies, addressing the informational challenges prevalent in the venture capital space. The firm provides a comprehensive suite of services, including direct and managed secondary investment opportunities, advisory services, and transaction facilitation, ensuring efficient and compliant processes. Manhattan Venture Partners targets well-capitalized companies with strong growth potential, primarily in sectors such as media, financial services, and information technology, leveraging its extensive experience to streamline transactions for private companies and their stakeholders.

Founded in Tel Aviv, Israel, iAngels is a women-led venture capital firm recognized for its active investment in Israeli startups. It operates a global crowdfunding platform connecting investors with technology startup opportunities worldwide. The firm invests across various sectors including software, healthcare, fintech, and consumer products.

Goodwater Capital is a California-based venture capital firm founded in 2014 that targets early-stage investments in consumer technology and related sectors, including housing, financial services, consumer products and services, healthcare, food, transportation, education, and entertainment. It backs exceptional entrepreneurs who create products and platforms that consumers love, with a focus on solving pressing problems and shaping the culture and global economy. Through its investments, Goodwater aims to enable startups capable of delivering broad, measurable improvements in billions of lives, reflecting a commitment to long-term positive impact.

BRM Group is a private equity and venture capital firm based in Tel Aviv, Israel, established in 1988. The firm focuses on early-stage investments across various sectors, including life sciences, healthcare, consumer goods, fintech, medtech, and technology-related companies. BRM Group aims to support Israel-related software, internet infrastructure, and communication ventures, emphasizing internet services, mobile applications, digital media, enterprise software, and medical devices. With a robust network of industry and financial experts, BRM Group is dedicated to providing streamlined investment decision-making processes to foster the growth of innovative companies in these fields.

Shenzhen Guozhong Venture Capital Management Co., Ltd. was established on December 21, 2015, and is based in Shenzhen, China. The firm manages the first entity fund of the Small Medium Enterprises Development Fund, which has a total size of 6 billion Yuan. With a registered capital of 100 million Yuan, its ownership is split between the Shenzhen Venture Capital Group (49%) and the management team of the Small Medium Enterprises Development Fund (51%). Guozhong Venture Capital focuses on investing in innovative technology, biomedical, healthcare, and TMT (technology, media, and telecommunications) sectors, aiming to support the growth of small and medium-sized enterprises in these dynamic fields.

Zero2IPO Group is an integrated service provider in China's venture capital and private equity sector. Headquartered in Beijing with offices in Shanghai, Shenzhen, Hong Kong and Silicon Valley, it operates a network-focused platform that sources deals, conducts market research, and provides financial advisory services. Through its subsidiaries, including venture investment arms, the group invests and manages funds to back high-potential, high-growth Chinese enterprises, co-investing with active venture funds and leading or co-leading early-stage startups. Its services encompass investment forums, training programs, and advisory offerings that connect entrepreneurs with investors, helping portfolio companies scale across sectors such as Internet, mobile applications, digital media, healthcare, and green technologies. Zero2IPO Group positions itself as a value-add partner in the venture capital ecosystem, leveraging its extensive China network to identify opportunities and support value creation.

Network Ventures is a Chicago-based venture capital firm founded in 2016 that focuses on providing funding to seed stage companies. The firm primarily invests in businesses within the internet and technology sectors, aiming to support early-stage companies as they develop and grow. By concentrating on these industries, Network Ventures seeks to foster innovation and facilitate the success of emerging entrepreneurs.

Founded in 2004 and based in Palo Alto, California, Uncork Capital is a venture capital firm focusing on seed-stage investments in SaaS, consumer goods, healthcare, and technology companies across the United States. The firm invests out of two funds: a $200M Seed fund and a $200M Opportunity fund for larger investments in mature portfolio companies.

Matrix Partners is a San Francisco-based venture capital firm founded in 1977 that backs technology companies from idea through Series A and beyond. The firm focuses on software, AI, B2B, consumer, fintech, health tech, infrastructure, and related sectors, with a global footprint in the United States, India, and China. Its team comprises former founders and operators who work closely with portfolio companies and often join boards to support growth. Matrix Partners has backed a broad slate of successful companies in its decades-long history, including Apple, FedEx, Oculus, Zendesk, HubSpot, Canva, and Postmates, illustrating a pattern of helping developers and builders scale toward IPO or strategic exits. The firm's China arm extends its early-stage and growth investments in the Chinese market, reinforcing its international reach.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. Headquartered in New York City with offices in London, Tel Aviv, and Palo Alto, it concentrates on growth-stage software, internet, and data services, with notable focus areas including fintech, cybersecurity, AI/ML, DevOps, and healthcare. Founded in 1995, Insight Partners manages over $75 billion in regulatory assets under management and has invested in more than 750 companies worldwide, with over 55 portfolio companies achieving an IPO. The firm combines capital with hands-on, right-sized software expertise to support portfolio companies on their growth journey from first investment to IPO.

LightShed Ventures is an early-stage venture capital firm based in New York, founded in 2021. It invests in startups across technology, media, telecom, and consumer sectors, with emphasis on B2B, B2C, and information technology companies, and provides capital and strategic guidance to help founders scale their businesses.

Explorer 1 Fund is a venture capital firm based in Los Angeles, California, founded in 2021. The firm focuses on investing in companies within the emerging space economy, targeting innovative ventures that operate in the space sector. Through its investments, Explorer 1 Fund aims to support the growth and development of businesses that contribute to advancements in space technology and exploration.

Kosmos Ventures is a prominent venture capital firm based in Perth, Australia, established in 2017. The company specializes in blockchain-based assets and has been an early supporter of notable projects like Algorand, Solana, Polkadot, and Oasis. Kosmos Ventures focuses on investments in the blockchain, infrastructure, cryptocurrency, and digital asset sectors, prioritizing large infrastructure initiatives while also backing successful decentralized finance (DeFi) and gaming finance (GameFi) projects. The firm maintains active involvement in major Layer 1 networks and contributes to their growth through validator staking in collaboration with partners.

Founded in 2013 by Drexel University students Yakir Gola and Rafael Ilishayev, Gopuff is a pioneering instant commerce platform that delivers essential products directly to consumers' doorsteps. Its extensive product range includes over-the-counter medicine, baby food, cleaning supplies, snacks, beverages, and select alcoholic drinks, ensuring customers can satisfy their needs and cravings promptly.

Founded in 2016, Climate Impact Capital is an impact investment firm based in Houston, Texas. It focuses on early-stage technology companies addressing climate change through innovations in energy, food, and water solutions.