MassChallenge is a global startup accelerator supporting early-stage entrepreneurs across various industries. Founded in 2009, it provides mentorship, resources, and networking opportunities through its programs worldwide.

Accomplice is a Boston-based venture capital firm, with an additional office in San Francisco, specializing in seed and early-stage investments in technology startups. It primarily invests in companies focused on cybersecurity, eSports, data analytics, SMB class software, emerging hardware platforms, and marketplaces. Accomplice uniquely leverages community platforms like AngelList, Boston Syndicates, and Maiden Lane to empower and fund exceptional founders. With a majority of its investments in Boston and additional investments throughout the U.S., Canada, and the E.U., Accomplice is one of the most active early-stage firms in New England.

Battery Ventures is a technology-focused investment firm founded in 1983 and based in Boston, Massachusetts. It engages in venture capital and private equity investments in technology companies, with emphasis on software (including application and infrastructure software), IT infrastructure technologies, consumer internet and mobile services, industrial technologies, and life science tools. The firm seeks to back category-defining businesses with potential for scalable growth, often supporting companies through multiple stages and across select global regions.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. The firm focuses on growth-stage software, internet, and data services, with emphasis on fintech, cybersecurity, artificial intelligence and machine learning, DevOps, and healthcare. Based in New York City with offices in London, Tel Aviv, and Palo Alto, Insight Partners has backed more than 750 companies worldwide and has more than 55 portfolio companies that have achieved an IPO. As of 2022, the firm reports over $75 billion in assets under management. It seeks to fund and work closely with visionary executives, providing practical, hands-on software expertise to support growth from initial investment through to IPO.

The Boston Foundation is a not-for-profit community foundation in Boston, established in 1915 as one of the oldest and largest in its field. It manages charitable assets, funds nonprofit organizations, and serves as a civic leader and convener to promote a thriving city and region where justice and opportunity are extended to everyone.

MassVentures is a venture capital firm based in Waltham, Massachusetts, established in 1978 as a quasi-public corporation by the Massachusetts Legislature. The firm focuses on providing seed and early-stage funding to high-growth startups, facilitating their transition from concept to commercialization. MassVentures invests primarily in sectors such as information technology, healthcare, cybersecurity, e-commerce, mobile, manufacturing, and robotics. With a governance structure that includes an independent Board of Directors and management by experienced venture capitalists, MassVentures leverages the state's entrepreneurial spirit and innovation centers to support the Massachusetts innovation economy. The firm also offers accelerator programs to further assist emerging companies in their growth journey.

Founded in 2015, Underscore.VC is a Boston-based venture capital firm focusing on seed to series A investments. It primarily invests in technology companies with an emphasis on sensor-related technologies, software for factories and home automation, healthcare infrastructure, data storage databases, and cloud-based marketing/commerce software.

Boston Seed Capital is a seed- and early-stage venture capital firm based in Massachusetts, with offices in Boston and Wellesley Hills. Founded in 2010, it focuses on funding internet-enabled and technology-driven startups across the United States, including consumer products, B2B software as a service, cybersecurity, e-commerce, big data, artificial intelligence and machine learning, marketplaces, and related services. The firm backs early-stage companies, often in information technology and SaaS, providing capital and strategic support to help companies scale from initial traction to growth.

Google is a multinational technology company renowned for its search engine, offering services such as Gmail, Google Drive, Google Docs, and YouTube. It specializes in advertising solutions through Google Ads and mobile operating systems with Android, while actively innovating in artificial intelligence and machine learning.

Samsung Venture Investment Corporation is the corporate venture arm of Samsung Electronics, founded in 1999 and based in Seoul. It maintains a global presence with activity in innovation hubs such as the San Francisco Bay Area, Boston, London, Tel Aviv, Bangalore, Tokyo, and Beijing, and it backs emerging technology startups across Europe, Asia, and North America. The firm sources and invests in technology companies at multiple stages, from early-stage to pre-IPO, focusing on areas including semiconductors, materials, mobile services, internet, software, security, and enterprise solutions, as well as bioengineering and medical tech. Its investment approach targets companies developing AI, robotics, augmented and virtual reality, cybersecurity, 5G, next generation displays, battery technology, digital health, and insurtech, among others, to support shaping future technologies.

Founded in Boston in 2004, RA Capital is an investment firm specializing in life sciences and drug development. Its team, with backgrounds in biology, chemistry, medicine, and industry experience, invests in early-stage companies with promising technologies and products across healthcare and life science sectors.

WindSail Capital Group, LLC is a private equity and venture capital firm based in Boston, Massachusetts, established in 2013. The firm specializes in providing growth capital to companies focused on energy innovation and sustainability across various industries. WindSail offers a range of financing solutions, including senior secured loans, junior secured loans, stretch loans, and bridge loans, primarily targeting U.S.-based businesses. With an investment strategy that emphasizes flexible financing options, WindSail aims to support companies that are either revenue-generating or in the early stages of commercial development. The firm typically invests equity ranging from $2 million to $8 million and debt from $2 million to $10 million, ensuring its portfolio companies have the necessary resources to facilitate growth while minimizing equity dilution.

Founded in 2000, General Catalyst is a venture capital firm specializing in early-stage and growth equity investments. It focuses on accelerating ideas, careers, and companies towards success by providing ongoing momentum and mentorship based on deep experience.

Salesforce is a cloud-based software company that provides enterprise customer relationship management software and applications on a subscription basis. It designs and develops cloud-based enterprise software for sales, customer service, marketing automation, e-commerce, analytics, and application development, offering a comprehensive suite including Service Cloud, Marketing Cloud, Commerce Cloud, MuleSoft for data integration, and the Salesforce Platform. Its Customer 360 platform unifies customer data across systems, apps, and devices to help organizations sell, service, market, and conduct commerce more effectively.

LaunchCapital, established in 2008, is a venture capital firm headquartered in New Haven, Connecticut, with additional offices in Boston, New York, and San Francisco. The company invests in early-stage startups, focusing on seed rounds with investments typically ranging from $50,000 to $150,000. LaunchCapital supports entrepreneurs across various sectors, including commerce, marketplace, consumer, media, entertainment, enterprise software, emerging tech, data, finance, healthcare, and medical technology. The firm employs two distinct investment strategies: LaunchCapital Ventures, which follows a traditional equity model for high-growth opportunities, and LaunchCapital Small Business, which offers a blend of equity and debt financing for businesses with linear growth expectations and local or regional reach.

Avalon Ventures is a venture capital firm established in 1983 with operations in San Diego and Boston. The firm concentrates on seed and early-stage investments in technology and life sciences companies across the United States. It supports founders pursuing disruptive ideas in rapidly changing markets and seeks opportunities in information technology, software, telecommunications, and biopharma areas. Avalon often collaborates with other investors to expand opportunities and provides strategic guidance during the critical development phase of portfolio companies. The firm emphasizes a hands-on approach, leveraging its entrepreneurs-turned-investors background to help early ventures navigate product, market, and regulatory challenges.

Accel is a venture capital firm founded in 1983 and based in Palo Alto, California, with additional offices in San Francisco, London, and Bangalore. It focuses on early and growth-stage technology startups, investing across software, cloud, data analytics, mobile technology, consumer services, fintech, security, healthcare, and information technologies. Accel seeks to partner with entrepreneurs to build world-class companies that define new categories and drive growth. Its portfolio includes notable technology companies such as Atlassian, Dropbox, Slack, Spotify, Etsy, Cloudera, DJI, Braintree, and Lookout Security, among others.

Estabrook Advisors is a financial services firm that offers investment and advisory services to individuals and business clients. It provides wealth management, financial planning, and M&A advisory, along with tax planning and bookkeeping, aiming to deliver tailored financial solutions and comprehensive investment strategies. Founded in 2011 and based in Boston, the firm focuses on helping clients manage assets, plan for growth, and navigate financial decisions through integrated advisory services.

Massachusetts Capital Resource Company, founded in 1977 and based in Boston, Massachusetts, serves as a private investment firm focused on addressing the funding gap for growing companies. The company provides risk capital in the form of mezzanine financing, long-term debt, and equity investments, specifically targeting emerging growth and middle-market firms. Its primary sectors of interest include manufacturing, distribution, service, and technology. By offering tailored investment solutions, Massachusetts Capital complements the financing available from senior lenders and equity investors, thereby supporting the growth and acquisition needs of companies operating in Massachusetts.

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

Founded in Toronto in 2007, Lumira Ventures is a venture capital firm focusing on investments in biotechnology, biopharmaceuticals, medical devices, digital health, and consumer health companies. With offices across North America, the firm invests primarily in Canada and the United States, typically allocating between USD 5 million to USD 15 million per investment. Lumira Ventures actively supports its portfolio companies by facilitating access to funding sources, partners, and market opportunities.

Founded in 2002, FlyBridge is a seed-stage venture capital firm based in Boston, Massachusetts. It invests primarily in computer hardware, software, SaaS, and big data sectors, aiming to leverage the power of community with entrepreneurs.

Whale Rock Capital Management, LLC is an employee-owned investment firm based in Boston, Massachusetts, established in March 2006. The firm specializes in managing pooled investment vehicles and primarily invests in public equity markets, with a significant focus on the United States. Whale Rock Capital employs a long/short equity strategy, concentrating its investments in the technology, media, and telecommunications sectors. The firm utilizes fundamental analysis, supplemented by external research, to inform its investment decisions.

Matrix Partners is a venture capital firm founded in 1977 and based in San Francisco that backs early-stage and Series A technology companies across sectors such as artificial intelligence, B2B software, consumer technology, fintech, health tech, infrastructure, and semiconductors. The firm emphasizes practical, founder-centered collaboration, often supporting concepts from idea stage through Series A and taking board seats to help portfolio companies scale. It operates globally, including Matrix Partners China, which focuses on long-term relationships with entrepreneurs in China and has a track record of IPOs and strategic exits. The team combines former founders and experienced investors to bring local execution and global perspective. Notable investments span across the technology landscape, reflecting a history of involvement with companies like FedEx, Apple, Oculus, Canva, Zendesk, HubSpot, Postmates, Fivetran, Sila, and GOAT, illustrating the firm’s ability to support companies from early development to scale.

Founded in 2010, BOLDstart Ventures is a venture capital firm based in Miami, Florida. It focuses on investing in early-stage technology companies, particularly those working on enterprise infrastructure and SaaS. The firm often partners with technical founders from the inception stage, providing lead investment and support to help them achieve product-market fit.

Walnut Ventures is a venture capital firm headquartered in Boston, Massachusetts, that focuses on investing in seed and early-stage companies, primarily within the information technology sector. The firm is particularly interested in areas such as home entertainment software, data processing, online services, and internet marketing. It typically invests between $250,000 and $1 million in companies located in the New England region and aims to take an active role by seeking a board seat in its portfolio companies. Established in 1997, Walnut Ventures comprises a network of experienced entrepreneurs and investors who are dedicated to helping talented entrepreneurs build sustainable businesses in rapidly growing markets. The firm offers not only financial investment but also support in refining business plans, enhancing management teams, developing financing strategies, and facilitating strategic partnerships.

ENIAC Ventures is an independent seed and early-stage technology focused venture capital firm based in New York, with activity across North America and Western Europe. It leads seed rounds and invests in software, mobile, artificial intelligence, fintech, enterprise, consumer, healthcare, and other transformative technologies, partnering with bold founders to help them bring products to market and pursue follow-on rounds. The firm combines capital with a hands-on platform that provides talent recruitment, public relations and marketing support, operations resources, business development and networking opportunities, and fundraising guidance and syndicate building. The team emphasizes a collaborative approach, acting as a founding partner to portfolio companies and leveraging its network to open doors and accelerate growth.

Morningside is a venture capital firm based in the greater Boston area, specializing in investments in companies that focus on innovative science and technology. Established in 1986 as a family office for the Chan family, Morningside emphasizes a long-term approach to company-building and maintains a strong commitment to ethical practices. The firm is staffed by a team of experienced investment professionals with expertise in various sectors, including life sciences, digital health, artificial intelligence, materials, and technology. In addition to its investment activities, Morningside is dedicated to philanthropic efforts, supporting education, research, and healthcare initiatives such as the Harvard T.H. Chan School of Public Health, UMass Chan Medical School, and the MIT Morningside Academy for Design.

Omega Funds is a Boston-based venture capital and private equity firm founded in 2004 that concentrates on early-stage investments in healthcare and biotech across North America and Western Europe, backing companies in life sciences, digital health, immunology, rare diseases, precision medicine, oncology, cybersecurity, and software-as-a-service.

Founded in 2019, Blindspot Ventures is a Boston-based venture capital firm focusing on seed investments in cross-vertical infrastructure and platform technologies. They partner with founders developing disruptive solutions to reshape industries.

Established in 2011 and headquartered in Boston, Gutbrain Ventures is an independent venture capital firm specializing in investments within the enterprise software sector.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in 1971, Schooner Capital is a Boston-based investment firm focusing on growth equity investments. It primarily invests in private companies across various stages and sectors, with a particular interest in alternative energy and clean tech within the United States.

Longwood Fund is a Boston-based venture capital firm that creates and invests in science-based companies developing novel solutions for important medical problems. The firm concentrates on healthcare and life sciences, including biotechnology, pharmaceuticals, oncology, and healthtech, supporting ventures from discovery through development with capital and strategic guidance. Established in 2010, Longwood seeks to translate laboratory advances into clinically meaningful products by backing companies built on strong scientific foundations and collaborations with leading research institutions. Through its investments, the firm aims to advance therapies and technologies that address unmet medical needs and improve patient outcomes.

Related is a real estate company, offering luxury apartment rentals and for sale condominiums in Manhattan, New York, Boston, Los Angeles, and more. Its collection of new urban landmarks includes luxury condominium and rental residences, affordable housing, large format retail centers, and mixed-use properties, including the crown jewel of its New York developments, Time Warner Center. Related pioneered the concept of commissioning architects to design residential properties by selecting Robert A.M. Stern to plan his firm’s first luxury condominium in New York City, The Chatham. In the development of Time Warner Center, Related combined super-luxury residences, the Mandarin Oriental Hotel and Residences, Jazz at Lincoln Center, the world headquarters of Time Warner and Related Companies, stylish retail, and a collection of four-star restaurants. Related is based in New York, N.Y.

Boston-based venture capital firm founded in 2005 that focuses on early-stage and select growth investments in information technology and related services. The firm backs enterprise IT companies, emphasizing information security, cloud infrastructure, data analytics, and software-as-a-service models, as well as technology-enabled business services and digital health, and it also targets healthcare IT, fintech, mobile software, and next-generation software. It prefers open source and SaaS delivery. Typically investing initial rounds of 2 to 5 million and totaling 6 to 10 million per company, it seeks board representation and often serves as lead or first institutional investor, with minority to majority stakes ranging from 20 to 80 percent. The firm reserves capital for opportunistic investments in more mature companies where its team has prior experience and focuses on opportunities in the Northeast United States.

186 Ventures is an early-stage technology investor and venture capital firm based in Boston, Massachusetts. Founded in 2018, it backs agile teams solving disruptive problems and Invests across consumer, enterprise, and technology sectors.

Mendoza Ventures is a venture capital firm based in Boston that focuses on seed and early-stage investments in financial technology, information technology, artificial intelligence and cybersecurity. Led by Adrian and Senofer Mendoza, the firm emphasizes diverse leadership in its portfolio, supporting startups led by immigrants, people of color, and women. Since its inception in 2016, Mendoza Ventures has built a team of operating partners from large organizations and engages strategic investors to help portfolio companies scale. The firm expanded with a San Francisco office in 2022 and has pursued a third fund anchored by Bank of America to back Series A to C rounds. Mendoza Ventures aims to back founders across the fintech and technology sectors, leveraging sector expertise and a network to help early-stage companies grow.

Founded in 1825, KeyBank is a major U.S. bank-based financial services company with approximately $93 billion in assets. It offers a range of retail and commercial banking, investment management, consumer finance, and investment banking products and services to individuals and businesses across the United States.

FinTech Sandbox is a Boston-based nonprofit accelerator established in 2014 that supports FinTech startups worldwide in overcoming barriers to product development. It addresses the high costs of financial data by providing entrepreneurs with free or discounted access to essential data feeds, APIs, and development resources. In addition to data access, FinTech Sandbox fosters growth by facilitating customer introductions, offering cloud hosting solutions, and creating a vibrant community that includes mentors, investors, and service providers. The organization also sponsors events and networking opportunities, enhancing connections within the FinTech ecosystem both locally and beyond.

Silversmith Capital Partners is a Boston-based growth equity firm founded in 2015 that partners with technology and healthcare companies to support growth and profitability. It targets investments in software, information technology and services, healthcare information technology and services, and other technology-enabled healthcare businesses, providing growth capital and strategic guidance to help companies scale, innovate, and expand market reach.

Tiger Global Management is a New York based investment firm that manages public and private market strategies to pursue technology-driven growth opportunities worldwide. Founded in 2001 by Charles (Chase) Coleman, the firm invests in leading global companies across various industries, with a particular emphasis on technology-enabled growth. In public markets it employs long/short and growth strategies, while in private markets it targets opportunities from early to late stage. The firm operates globally, including the United States, China, India, Latin America, and Eastern Europe, and works with portfolio companies across their lifecycle to drive long-term value.

Logos Capital is a hedge fund manager based in San Francisco, founded in 2019, specializing in fundamental biotechnology investments. The firm combines in-house data analytics with scientific and clinical expertise to rigorously evaluate potential therapies and treatment platforms. It uses fundamental and sector-focused equity strategies and applies statistical modeling of clinical data to strengthen diligence and identify compelling opportunities with the aim of delivering uncorrelated returns. By integrating medical, scientific, and statistical perspectives, Logos Capital seeks to deepen its conviction in investment ideas and maintain disciplined risk management.

Founded in 1973, Abingworth is an international investment group dedicated to collaborating with life sciences entrepreneurs. With over $1 billion under management, it invests across all stages of development and sectors within the life sciences industry. The company supports its portfolio companies with a team of 27 based in London, Menlo Park, and Boston.

Pillar VC is a Boston-based venture capital firm established in 2016 that provides early capital and supports founders from inception through growth. It backs university spinouts led by first-time founders as well as serial entrepreneurs, aiming to build meaningful, scalable companies. The firm focuses on high-potential ventures across machine intelligence, AI, hardware, enterprise software, blockchain, quantum, digital health, and synthetic biology, and offers connections, coaching, and a community to help founders develop personally and professionally. Pillar VC is open to ventures of various types and emphasizes hands-on support and collaboration to accelerate progress.

Founder Collective is a seed and early-stage venture capital firm founded in 2009 with roots in Cambridge, Massachusetts and offices in New York. The firm is built by entrepreneurs who have founded and exited technology companies, and it aims to back founders by providing practical capital and guidance to navigate the risks of venture funding. It concentrates on early investments in technology companies, with an emphasis on software and information technology, and it makes bets across the United States and beyond, though its roots are on the East Coast. The team partners with portfolio companies to help them scale, often supporting startups that seek modest initial financings. Through its network and hands-on approach, Founder Collective seeks to partner with ambitious teams to grow durable, technology-driven businesses.

Romulus Capital, established in 2008, is a Boston-based venture capital firm that specializes in seed and early-stage investments, primarily in technology startups across the United States, with a focus on the East Coast, and select opportunities in London, Israel, and India. The firm invests in a broad range of sectors, including software, big data, healthcare IT, education, and energy technology, with a preference for B2B and B2B2C models. Romulus Capital typically invests between $100,000 and $1 million initially, with the ability to scale up to $5 million over time as companies grow. The firm is known for its company-building approach, partnering with brilliant, often first-time entrepreneurs frequently affiliated with top universities and incubators.

HarbourVest Partners is a global investment firm specializing in private markets. Established in 1980, the company provides institutional clients worldwide with innovative solutions through primary fund investments, secondary purchases, and direct co-investments across venture capital, buyouts, growth equity, and other alternative asset classes.

Founded in 2013, Bolt is a venture capital firm based in Boston, Massachusetts. It specializes in seed and early-stage investments in technology and data-driven sectors.