Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, established in 2013. It targets individual accredited investors who previously had limited access to venture capital by enabling alumni from top entrepreneurial schools to invest together in ventures led by fellow alumni. The firm backs companies with an alumni connection and an institutional lead investor with sector expertise. It offers focused funds that provide accredited investors access to a diversified venture portfolio by type, sector, stage, and geography. The organization engages in seed, early-stage, and late-stage pre-IPO investments across technology, consumer, financial services, health care, life sciences, and other sectors.

Antler is a global venture capital firm based in Singapore that backs early-stage technology companies. It runs incubation programs and provides a global community of co-founders, access to talent, expert advisors, expansion support, and capital to help startups grow. The firm targets a broad range of sectors, including healthcare, finance, software, energy, consumer and B2B technologies, and operates through regional programs across Europe, the United States, the United Kingdom, Southeast Asia, India, Africa, and beyond.

SOSV is a global venture capital firm based in Princeton, New Jersey, founded in 1995, that focuses on seed to growth investments in deep technology across health, environmental tech, hardware, robotics, and cross border software, with a particular emphasis on Asia. The company runs accelerator style startup development programs, including HAX and IndieBio, which provide facilities, engineering resources, and lab equipment to help founders accelerate product development, acquire customers, and attract later stage funding. SOSV pursues a limited number of high potential startups, offering extensive hands on support to speed commercialization and scale, and aims to back innovations that improve human and planetary health.

StartUp Health is a health innovation platform founded in 2011 that supports a global portfolio of health technology companies through a network of entrepreneurs known as Health Transformers. Its mission is to achieve health moonshots by advancing solutions across Access to Care, Cost to Zero, Cure Disease, End to Cancer, Women’s Health, Children’s Health, Nutrition and Fitness, Brain Health, Mental Health and Happiness, Addiction, Longevity, and Pandemic Response. The organization oversees more than 330 portfolio companies across six continents and 26 countries, working with leading health systems and investors to accelerate adoption and impact. By connecting entrepreneurs with health systems, researchers, and investors, StartUp Health aims to improve the health and wellbeing of people worldwide and transform healthcare delivery over a multi-decade timeframe.

General Catalyst is a venture capital firm founded in 2000 that provides early-stage and growth equity investments in technology companies. It supports portfolio companies with momentum and mentorship to accelerate growth toward long-term success and typically engages across seed to growth stages, potentially taking minority or majority stakes. The firm targets a broad range of sectors enabled by software and technology, including consumer, enterprise, fintech, crypto, healthcare IT, and related areas, and maintains a multi-region presence with offices in North America and Europe to back companies as they scale globally.

Gaingels is a venture investment organization focused on LGBTQ+-founded and led companies and their allies, investing across stages from pre-seed to pre-IPO and maintaining a global portfolio. Founded in 2014 and based in New York, it operates as a syndicate with more than 130 portfolio companies and around $70 million deployed. The organization supports inclusive leadership by backing ventures that promote diverse C-suite and board representation and actively assists portfolio companies in recruiting diverse executive talent. It also fosters a global community of industry leaders, investors, operators, and entrepreneurs who pursue positive social change through business and successful investments.

What If Ventures is a venture capital firm based in Frisco, Texas, that backs startups in healthcare and aerospace and defense. Founded by Stephen Hays around 2019–2020, the firm targets early-stage companies from seed to Series C and has deployed nearly $100 million across more than 80 healthcare startups. Hays' background as a U.S. Army veteran and West Point graduate, with prior experience in aerospace and defense investment banking, informs a focus on large, fragmented markets with complex regulation and significant government and commercial customers. The firm seeks to fund disruptive innovations that can improve lives or enhance safety, tackling industries where new entrants historically struggle to gain traction against established incumbents.

City Light Capital is a New York-based venture capital firm founded in 2004 that conducts early- and growth-stage investments in United States companies. It backs teams building category-defining solutions across education, safety and care, and the environment, as well as technology-enabled sectors such as digital health, climate, energy, agriculture, and IoT. The firm pursues impact-oriented investments designed to scale revenue and improve lives by partnering with experienced entrepreneurs to build durable, market-leading businesses. City Light emphasizes aligning financial returns with social and environmental outcomes and acts as an active, hands-on investor across a broad range of sectors addressing societal challenges.

Right Side Capital Management is a San Francisco-based venture capital firm founded in 2010 that invests in early-stage technology startups. It specializes in pre-seed and seed rounds for capital-efficient companies, with a focus on the United States and Canada and occasional activity in Western Europe, Israel, Australia, and New Zealand. The firm typically makes 75 to 100 investments per year, with round sizes from 50,000 to 500,000 and pre-money valuations ranging from 1,000,000 to 3,500,000. Portfolio companies are typically located outside the San Francisco Bay Area and New York City, and the firm aims to provide a clear yes or no on opportunities within about two weeks.

Mystic Ventures is an early-stage venture capital firm based in Los Angeles, founded in 2021. It focuses on investing in psychedelic medicine and related mental health, neuroscience, and CNS therapies, prioritizing pre-seed and seed-stage startups that develop psychedelic experiences and treatments. The firm emphasizes supporting founders with access to a broad network of medical professionals, academics, and industry experts to validate ideas and accelerate growth. By backing world-class teams at the early stages of this nascent field, Mystic Ventures seeks to advance innovative therapies and expand opportunities in mental health care and consciousness research. The firm aims to leverage its industry connections and resources to drive deal flow and help portfolio companies reach milestones while navigating regulatory and clinical development pathways.

Goodwater Capital is a California-based venture capital firm founded in 2014 and headquartered in Burlingame. It focuses on early-stage investments in consumer technology and related sectors, including housing, financial services, software, healthcare, education, and entertainment. The firm seeks to empower exceptional entrepreneurs solving pressing problems and believes consumer technology can reshape culture and the global economy. By backing founders who create products and platforms that consumers love, Goodwater aims to drive significant, scalable impact and improve billions of lives.

Optum is a health services and innovation company dedicated to helping people live healthier lives. It designs a healthcare system that connects people, places, and ideas across the ecosystem to deliver personalized care, including medication, healthcare financial services, and guidance, along with technology and services for health plan providers. The company offers a broad range of medical services, including family medicine, internal medicine, pediatrics, women's health, substance use treatment, and mental health, as well as care for common conditions of the eyes, ears, skin, and nervous system. By integrating data, insights, and digital tools, Optum seeks to improve access, care coordination, and the efficiency of the medical system for patients, providers, and employers in collaboration with health plans and other partners.

PsyMed Ventures is a San Francisco-based venture capital firm founded in 2020 by Matias Serebrinsky and Dina Burkitbayeva. It backs early-stage companies focused on mental and brain health, including psychedelics medicine and new compounds, neurotechnology and human augmentation, precision psychiatry, and digital therapeutics.

GreyMatter is a venture capital firm based in San Francisco, California, founded in 2021, focused on investing in mental health and emotional well-being companies and supporting bold founders developing solutions in mental health, wellbeing, and related areas.

Everywhere Ventures is a New York-based venture capital firm founded in 2017. It operates as a community-powered, early-stage investor that combines capital, mentorship, and operational experience from founders and operators across ten micro funds. The firm funds pre-seed startups globally, with emphasis on purpose-driven teams in the money, health, and work verticals, and typically participates in the first financing round. Its limited partners include more than 500 founders and operators who provide hands-on guidance and contribute to the fund's capital. The model centers on founders helping founders, aiming to accelerate the next generation of entrepreneurs through a collaborative platform rather than a traditional fund structure.

.406 Ventures is a Boston-based venture capital firm founded in 2005 that specializes in early-stage investing in enterprise information technology and services. The firm backs B2B software, cybersecurity, IT security and infrastructure, data and cloud technologies, technology-enabled business services, digital health, fintech, big data, and artificial intelligence, with a geographic focus on the Northeast United States. It often acts as lead or first institutional investor in de novo and early-stage rounds and supports portfolio companies through growth with follow-on investments. Typical initial commitments range from 2 to 5 million dollars, with total investments of about 6 to 10 million per company. The team emphasizes practical industry experience and networks to help companies scale.

Lionheart Ventures is a venture capital firm founded in 2019 and based in San Francisco, California. It operates as a global seed-stage investor focused on mitigating civilizational risk by backing transformative technologies, with emphasis on artificial intelligence and frontier mental health innovations. The firm finances early-stage companies across information technology, AI, climate technology, financial technology, and health technology, including wearables, and pursues impact investing. Lionheart supports exceptional, ethical founders whose technologies have the potential to meaningfully benefit humanity while delivering attractive returns for its backers.

Oak HC/FT is a Stamford, Connecticut-based venture and growth equity firm that concentrates on healthcare information services and financial technology. It supports entrepreneurs with strategic counsel, board‑level participation, and access to an extensive network of industry leaders to drive transformation in these sectors. The firm draws on Oak Investment Partners’ sector expertise to build and grow innovative businesses, with a history of notable exits and large valuations. Founded in 2014, Oak HC/FT targets both growth‑stage and early‑stage companies in the United States, aiming to deliver strong value for investors.

The Blue Venture Fund is the corporate venture capital arm of the BlueCross BlueShield Association, based in Chicago. It invests in healthcare technology, healthcare services, and clinical sciences companies with the potential to improve care quality, patient experience, and cost efficiency, and seeks opportunities that align with the needs of BCBS member companies and their policyholders to foster innovation within the healthcare system.

FJ Labs is a New York-based venture capital firm founded in 2015 by Fabrice Grinda. It is stage-agnostic and focuses on marketplaces and consumer-facing startups, making seed and Series A investments. Typical checks range from 50,000 to 5,000,000 dollars. The firm supports early-stage companies across sectors such as e-commerce, fintech, ad tech, mobile, and software-as-a-service, seeking opportunities with high growth potential in the United States and internationally. Its portfolio includes a mix of consumer brands and marketplace platforms, reflecting an emphasis on business models that connect buyers and sellers or enable direct consumer experiences. FJ Labs aims to back entrepreneurs building scalable, disruptively positioned products and services, often partnering with founders early in their development to help accelerate growth.

XEIA Venture Partners is a venture capital firm based in San Francisco, founded in 2021. It targets investments in life sciences, artificial intelligence, hardware, software, deep tech, and health tech sectors.

Wisdom Ventures is a California-based venture capital firm founded in 2021 that serves as a seed-stage fund investing globally in healthcare, compassion, and wellness startups. It relies on a partner-led team with extensive networks and a proven track record as investors, experts, and leaders to identify and support innovative ventures in these sectors.

Palo Santo is a Chicago-based venture capital firm founded in 2020 that concentrates on therapeutic, well-being, and mental healthcare sectors. It seeks to back high-growth companies in areas such as biotechnology and drug development, health care services, and digital health, prioritizing teams with experience and ethical leadership to advance mental health and related conditions.

Khosla Ventures is a California-based venture capital firm founded in 2004 by Vinod Khosla. The firm backs entrepreneurs with venture assistance, strategic guidance, and capital, focusing on bold, early-stage technology companies. It invests across sectors including AI, climate and sustainability, enterprise software, consumer technologies, fintech, digital health, medtech and diagnostics, therapeutics, and frontier technologies. Based in Menlo Park, the firm manages several funds to support startups across stages, prioritizing ventures that address large markets and have potential for significant social and economic impact.

Refactor Capital is a Burlingame, California-based venture capital firm focusing on seed- and early-stage investments in hard technology, biotechnology, health, climate, and related sectors. The firm is led by Zal Bilimoria, a former partner at Andreessen Horowitz and a veteran product and engineering executive with experience at Google, Netflix, and LinkedIn, who typically leads seed rounds with checks in the 1–2 million range.

Flare Capital Partners is a Boston-based venture capital firm focused on healthcare technology and related life sciences. It invests in early-stage and growth companies across the United States, targeting healthcare technology systems, digital health, big data and analytics, medical devices, diagnostics, and other health care innovations that enable value-based care and data-driven patient outcomes.

Felicis Ventures is a Menlo Park, California-based venture capital firm that backs founders building iconic, boundary-transcending companies. It focuses on early-stage investments across software, information technology, consumer internet, AI, health, and security, and complements capital with active mentoring and advisory support. The firm pursues global opportunities, maintains a diverse portfolio, and has backed over 120 technology companies, with around 50 exits. It was founded by Aydin Senkut, a former Google executive, and emphasizes reinvention of core markets and frontier technologies.

Noetic Fund is a Toronto-based venture capital firm that invests globally in emerging technologies across molecular therapeutics, digital health, medical devices, and wellness, with a focus on mental health and central nervous system related conditions. It supports companies advancing alternative therapies, modalities, and sciences aimed at improving mental, emotional, psychological, and physical health.

SFC Capital is a United Kingdom-based venture capital firm founded in 2012 that makes early-stage investments in UK startups, including pre-seed and seed rounds. It backs companies across sectors such as software, technology, e-commerce, consumer, enterprise, green tech, medical technology, and hospitality, providing capital plus strategic guidance to support growth and product development. The firm operates a model that combines an angel network with seed funds to back SEIS- and EIS-qualifying businesses, aiming to offer exposure to a diversified portfolio while delivering hands-on support to portfolio companies.

Ulu Ventures is a Palo Alto, California-based seed- and early-stage venture capital firm focused on technology-driven startups across IT, software, internet-enabled services, EdTech, FinTech, IoT, digital media, and related sectors in the United States, with a Bay Area emphasis. Founded in 2008, the firm backs diverse entrepreneurial teams and frequently co-invests with other angels or venture funds in early rounds. Ulu is noted as the first Latina-led venture fund in Silicon Valley and is among the largest in the country by assets under management, with over $200M.

8VC is a technology and life sciences investment firm based in San Francisco that partners with founders to develop transformational technologies. The firm aims to create long-term economic and societal value through its investments, spanning healthcare, energy, consumer goods, financial services, infrastructure, information technology, manufacturing, enterprise, logistics, defense, and other sectors. By backing ambitious teams and providing strategic support, 8VC seeks to enable industry transformation and global innovation.

Calm/Storm Ventures is a Vienna-based boutique venture capital firm and founder network founded around 2019–2020. It makes early- and growth-stage investments across Europe and the United States, with a focus on digital health, health tech, healthcare, software, AI, fintech, and related sectors. The firm emphasizes health and wellbeing solutions and supports entrepreneurs through lifelong learning, empowering them with unique access to successful founders.

Sequoia Capital is a venture capital firm founded in 1972 and based in Menlo Park, California. It pursues investments across multiple sectors, including information technology, healthcare, manufacturing, mobile, nanotechnology, financial services, internet, energy, media, and retail, and provides early to growth-stage funding coupled with strategic support to help founders build lasting, category-defining companies.

WPSS.bio is a New York-based venture capital firm, founded in 2019, that invests in companies developing diagnostics and treatments for brain health and central nervous system health.

Bossa Invest is a venture capital firm based in Sao Paulo, Brazil, founded in 2011, that manages investment portfolios and provides asset management services to clients across sectors, with a focus on software as a service companies, and analyzes market trends to inform its investment decisions while operating in finance, technology, and real estate.

Jumpstart Foundry is a venture capital firm and accelerator based in Nashville, Tennessee, that funds and supports early-stage healthcare companies. It connects portfolio startups with industry stakeholders and provides guidance on strategic marketing, talent and growth, while operating a 14-week core program and a six-week micro-accelerator for startups, as well as a corporate-focused micro-accelerator. The firm concentrates on healthcare information technology, consumer health products and services, tech-enabled services, and diagnostic devices in the United States, aiming to accelerate growth, market adoption, and collaboration with industry leaders.

F-Prime Capital is a venture capital investment firm based in Cambridge, Massachusetts. Founded in 1969 with roots in Fidelity Investments, it backs entrepreneurs across technology and life sciences, investing in sectors such as crypto, enterprise information technology, fintech, frontier technologies, health information technology and services, medtech and therapeutics, with a global reach across the Americas, Europe and Asia.

ARCH Venture Partners is a United States-based venture capital firm founded in 1986 and headquartered in Chicago, Illinois. The firm focuses on science-driven companies, with a track record of commercializing technologies developed at academic research institutions and national laboratories. It primarily invests in life sciences, biotechnology, pharmaceuticals, healthcare technology, and related sectors, and also backs software, materials, clean tech, and information technology across early to growth stages. ARCH emphasizes relationships with scientists and entrepreneurs, often taking early stakes and supporting subsequent rounds to help market entry and scale. The firm has raised multiple venture funds totaling several billion dollars and maintains a national and international reach with offices across North America.

Town Hall Ventures is a New York-based venture capital firm founded in 2018 that backs healthcare technology companies across the United States. It seeks to transform the U.S. health care system by partnering with entrepreneurs who aim to improve care delivery and health outcomes for underserved and high-need populations through technology-enabled solutions.

Polaris Partners is a Boston-based venture capital firm with offices in Boston and San Francisco that backs technology and life sciences companies across the United States and Europe. Founded in 1996, the firm partners with repeat entrepreneurs to support companies through multiple stages, from inception to growth, with a focus on software, healthcare information technology, digital health, life sciences, biotechnology, pharmaceuticals, genomics, and related sectors. Its investments span the business-to-business and business-to-consumer markets, software as a service, and other technology-enabled solutions, aiming to build durable platform companies and address significant needs in healthcare and technology.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. Headquartered in New York City with offices in London, Tel Aviv, and Palo Alto, it concentrates on growth-stage software, internet, and data services, with notable focus areas including fintech, cybersecurity, AI/ML, DevOps, and healthcare. Founded in 1995, Insight Partners manages over $75 billion in regulatory assets under management and has invested in more than 750 companies worldwide, with over 55 portfolio companies achieving an IPO. The firm combines capital with hands-on, right-sized software expertise to support portfolio companies on their growth journey from first investment to IPO.

Founded in 2020, re.Mind Capital is a venture capital firm based in Sliema, Malta. It seeks to back companies delivering innovative solutions to global mental health crises, with a focus on neuroscience and life sciences. It is the mental health venture capital arm of serial entrepreneur and investor Christian Angermayer and his family office Apeiron Investment Group.

Frist Cressey Ventures is a Nashville-based venture capital firm focused on healthcare and digital health. Founded in the mid-2010s, it makes early- and growth-stage investments in technology and service businesses that offer viable solutions to improve quality of care, system integration, patient outcomes, and population health. The firm emphasizes value-added partnerships to accelerate growth and scale within the healthcare sector.

Maverick Capital is a global investment firm established in 1993 that manages capital through long/short hedged equity strategies and private investments, with offices in New York, San Francisco, London, Hong Kong, Philadelphia and Dallas. The firm seeks to grow and preserve capital for qualified investors, conducting deep fundamental research and actively partnering with portfolio companies to support growth, including deploying resources and taking board seats. Maverick Capital also operates Maverick Ventures, its venture arm based in San Francisco, which funds startups from seed through growth across healthcare, software and deep technology, leveraging the parent firm’s resources and experience to help entrepreneurs build scalable businesses.

HealthTech Capital is a private investor group that funds and mentors healthtech startups at the intersection of healthcare, computing, and mobility. The group aims to foster an ecosystem by connecting clinical providers, venture firms, and other strategic industry players to support healthtech innovation. Founded in 2010 and based in Los Altos Hills, California, it operates as an angel group investing in healthtech startups.

The Ukrainian Startup Fund was established to support the local startup ecosystem. It has become the largest angel investor in Ukraine, having funded 130 startups and maintaining the most comprehensive database of local ventures and stakeholders, with over 3,000 applications processed.

Joyance Partners is a San Francisco-based venture capital firm that backs early-stage startups in technology, health tech, consumer, internet, and mobile sectors across North America, Europe, and Asia. Founded in 2012, the firm seeks companies that, through science and technology, cultivate joy and improve how people live, with emphasis on health and consumer applications from pre-seed to Series A.

Able Partners is a New York-based venture capital firm founded in 2016 that invests in disruptive healthcare, care economy, consumer wellbeing, and connection and community sectors. The firm aims to support entrepreneurs and brands through partnerships, drawing on the founders’ experiences to help them reach their goals. It emphasizes close collaboration with portfolio companies and maintains flexibility in growth and exit paths to accommodate diverse trajectories.

Jazz Venture Partners is a San Francisco-based venture capital firm founded in 2015 that backs companies at the intersection of digital technology and neuroscience. It invests in technologies that extend human performance, including augmented reality, virtual reality, immersive gaming, artificial intelligence, and closed-loop human-computer systems. The firm seeks opportunities across health, mind-body wellness, peak mental and physical performance, accelerated learning and training, sports, and entertainment, and leverages a multidisciplinary team with backgrounds in investment, entrepreneurship, neuroscience, and technology to support portfolio companies.

Founder Collective is a seed- and early-stage venture capital firm founded in 2009 by entrepreneurs who have built and exited technology companies. Headquartered in Cambridge, Massachusetts, with an office in New York, the firm makes early investments across the United States and globally. It is industry-agnostic but prefers ventures with an information technology component, including software and TMT-enabled businesses. The firm focuses on supporting founders at the seed and early stages, drawing on the experience of its partners who have firsthand startup experience.